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Clinical Trials/NCT06092671
NCT06092671
Recruiting
Not Applicable

Effect of Family-centred Perioperative Care for Anaesthesia on Incidence of Emergency Delirium in Children After Surgery: a Protocol for a Randomised Controlled Trial

Second Affiliated Hospital of Wenzhou Medical University1 site in 1 country444 target enrollmentOctober 24, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Complications
Sponsor
Second Affiliated Hospital of Wenzhou Medical University
Enrollment
444
Locations
1
Primary Endpoint
The incidence of emergency delirium
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

Emergence delirium (ED) stands out as a prevalent postoperative complication among paediatric patients, correlating with extended hospitalization periods, escalated healthcare expenses, and increased incidence of postoperative maladaptive behaviours (POMBs). There is a lack of well-established pharmacological or non-pharmacological interventions demonstrating efficacy in reducing the occurrence of ED. Therefore, our objective is to assess the potential of family-centred perioperative care for anaesthesia (FPCA) in mitigating the incidence of ED in children, compared with routine anaesthesia.

Registry
clinicaltrials.gov
Start Date
October 24, 2023
End Date
December 1, 2026
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Second Affiliated Hospital of Wenzhou Medical University
Responsible Party
Principal Investigator
Principal Investigator

TING LI

Principal Investigator

Second Affiliated Hospital of Wenzhou Medical University

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

The incidence of emergency delirium

Time Frame: At the time patient awake from anesthesia after the sugery; 5min after awake; 15min after awake; 25min after awake;

The incidence of emergency delirium will be evaluated by the Pediatric Anesthesia Emergency Delirium scale (PAED). When the child wakes up in the PACU (the child can stay awake for more than 10 seconds), and 5min, 15min, 25min after waking up, a trained researcher will evaluate the PAED score (the maximum scores ≥10 will be diagnosed as ED).

Secondary Outcomes

  • The severity of emergency delirium(At the time patient awake from anesthesia after the sugery; 5min after awake; 15min after awake; 25min after awake;)
  • The incidence of postoperative maladaptive behaviours(at postoperative days 1, 2, 3, 7±2, 14±3 days and 3 months ±5 days after surgery)
  • Sleep quality(Baseline before surgery; at 7±2, 14±3 days and 3 months ±5 days after surgery)
  • Quality of life score(Baseline before the surgery and at 14±3 days and 3 months ±5 days after surgery.)
  • Compliance of anaesthesia induction(The period anaesthesia induction.)
  • Postoperative pain score(At the time patient awake from anesthesia after the sugery; 5min after awake; 15min after awake; 25min after awake.)
  • Preoperative anxiety of children(Baseline before surgery, in the preoperative holding area and during induction of anaesthesia.)
  • Preoperative anxiety of parents(Baseline before surgery, in the preoperative holding area and during induction of anaesthesia.)

Study Sites (1)

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