Perioperative Risk Factors for Postoperative Delirium in Children Following General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- The presence of delirium in post anesthesia care unit (PACU) and in ward determined by RASS-PAEDS criteria
研究概览
简要总结
Despite recent advances in postoperative delirium research, the proportion of children with postoperative delirium is still high. Although postoperative delirium is a frequent complication and is associated with the need for more inpatient hospital care and longer length of hospital stay, little is known about risk factors for recovery room delirium (RRD) occurred in postanaesthesia care unit. The aim of the study was to determine pre- and intraoperative risk factors for the development of RRD among children undergoing non cardiovascular surgery.
详细描述
Recovery room delirium (RRD) defined as delirium occurred in PACU was diagnosed according to RASS-PAEDS criteria. Pre-, intra-, and postoperative data of patients undergoing elective non cardiovascular surgery were prospectively collected, univariate and multivariate logistic regression were performed to find the risk factors related to postoperative delirium.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 3 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •between 3 to 12 years old
- •elective non-cardiovascular surgery
- •general anesthesia
排除标准
- •under regional anaesthesia
- •instable vital sign
- •without consent form
- •underwent neurosurgery
- •history of primary neurologic diseases
- •stayed less than 10min in PACU
- •received general anaesthesia but recovered in locations outside the recovery room
结局指标
主要结局
The presence of delirium in post anesthesia care unit (PACU) and in ward determined by RASS-PAEDS criteria
时间窗: at 1, 8, 16, 24, 48 and 72 postoperative hour
次要结局
- Maximal and minimal heart rate in PACU(every 15 min during PACU stay)
- Pulse Oximeter Oxygen Saturation (SpO2) in PACU(every 15 min during PACU stay)
- Hospital-length of stay(before discharge)
- Total health care fees(during hospital stay)
- Quality of recovery measured by PACBIS criteria(at 1, 8, 16, 24, 48 and 72 postoperative hour)
研究者
Wei Mei
Associate Professor
Huazhong University of Science and Technology