Perioperative Risk Factors for Postoperative Delirium in Children Following General Anesthesia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Delirium, Postoperative
- Sponsor
- Huazhong University of Science and Technology
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- The presence of delirium in post anesthesia care unit (PACU) and in ward determined by RASS-PAEDS criteria
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
Despite recent advances in postoperative delirium research, the proportion of children with postoperative delirium is still high. Although postoperative delirium is a frequent complication and is associated with the need for more inpatient hospital care and longer length of hospital stay, little is known about risk factors for recovery room delirium (RRD) occurred in postanaesthesia care unit. The aim of the study was to determine pre- and intraoperative risk factors for the development of RRD among children undergoing non cardiovascular surgery.
Detailed Description
Recovery room delirium (RRD) defined as delirium occurred in PACU was diagnosed according to RASS-PAEDS criteria. Pre-, intra-, and postoperative data of patients undergoing elective non cardiovascular surgery were prospectively collected, univariate and multivariate logistic regression were performed to find the risk factors related to postoperative delirium.
Investigators
Wei Mei
Associate Professor
Huazhong University of Science and Technology
Eligibility Criteria
Inclusion Criteria
- •between 3 to 12 years old
- •elective non-cardiovascular surgery
- •general anesthesia
Exclusion Criteria
- •under regional anaesthesia
- •instable vital sign
- •without consent form
- •underwent neurosurgery
- •history of primary neurologic diseases
- •stayed less than 10min in PACU
- •received general anaesthesia but recovered in locations outside the recovery room
Outcomes
Primary Outcomes
The presence of delirium in post anesthesia care unit (PACU) and in ward determined by RASS-PAEDS criteria
Time Frame: at 1, 8, 16, 24, 48 and 72 postoperative hour
Secondary Outcomes
- Maximal and minimal heart rate in PACU(every 15 min during PACU stay)
- Pulse Oximeter Oxygen Saturation (SpO2) in PACU(every 15 min during PACU stay)
- Hospital-length of stay(before discharge)
- Total health care fees(during hospital stay)
- Quality of recovery measured by PACBIS criteria(at 1, 8, 16, 24, 48 and 72 postoperative hour)