A study to understand role of early intervention, delivered by parents, to children who may later develop autism or other related conditions.

Phase 2

Conditions: Health Condition 1: F840- Autistic disorder

Registration Number: CTRI/2022/07/043681

Lead Sponsor: Dr Shoba Sreenath Meera

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Subjects with an older sibling fulfilling criteria for ASD based on Social Communication Questionnaire and/or clinical best estimate diagnosis-DSM 5 guidelines

Subjects with atypicalities identified by age appropriate assessments (for example First Year Inventory), or parental concerns or parents wishing to enroll their infant in the intervention

Subjects between the ages of 9 to 18 months

at least one parent willing to participate in the parent mediate intervention

Subjects whose primary language environments are Kannada, Hindi, English

Parents who have access to basic technology including a device ( for example laptop or smart phone) and adequate internet connectivity ( wifi, 4G mobile internet) to support video conferencing platforms like zoom.

Exclusion Criteria

Subjects with significant medical conditions known to affect brain development like Downs syndrome

Diagnosis of sensory impairment like hearing loss

Less than 2500 grams of birth weight

Perinatal birth injury secondary to birth complications like asphyxia

First degree relative with psychosis, schizophrenia or bipolar disorder based on family interview for genetic studies.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Score of Sensitive Responsiveness global rating scale - Manchester Assessment for Caregiver-Infant Interaction (MACI-Infant) <br/ ><br>Timepoint: T1-Baseline <br/ ><br>T2-12 Weeks after intervention <br/ ><br>

Secondary Outcome Measures