A COMPARATIVE STUDY ON THE EFFECT OF ALCOHOL-BASED HAND SANITIZERS IN SPRAY AND GEL FORMULATION ON THE SKIN OF THE HANDS

Phase 1

Recruiting

• Conditions: Healthy human volunteers; Alcohol-based hand sanitizer; Hand hygiene; Ethanol

• Registration Number: TCTR20220624001
• Lead Sponsor: Faculty of Medicine, Srinakharinwirot University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-24
• Study Completion: 2022-07-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 38

Inclusion Criteria

1. Age of more than or equal to 18 years old
2. Able to be followed up as appointed
3. Willing to give an informed consent

Exclusion Criteria

1. Having history of allergy to the component of product in study which symptoms are pruritic papules without burning sensation or pain at area contacting with alcohol-based hand sanitizers
2. Having hand eczema
3. Currently using an anti-inflammatory agent including tropical, oral, or injected form

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hand irritation Day 0, 3, 5, 7, 14, 21 Subjective Larson skin assessment

Secondary Outcome Measures

Name	Time	Method
Hand irritation Day 0, 3, 5, 7, 14, 21 Frosch and Kligman observer skin assessment,Skin barrier status Day 0, 3, 5, 7, 14, 21 Transepidermal water loss,Skin hydrating status Day 0, 3, 5, 7, 14, 21 Skin capacitance,Patient tolerability and acceptability Day 21 WHO protocol for evaluation and comparison of tolerability and acceptability