MedPath

A Trial of an Integrated Clinic-community Intervention in Children and Adolescents With Obesity (Hearts and Parks)

Not Applicable
Completed
Conditions
Childhood Obesity
Pediatric Obesity
Cardiovascular Risk Factor
Quality of Life
Interventions
Behavioral: Hearts & Parks
Registration Number
NCT03339440
Lead Sponsor
Duke University
Brief Summary

The investigators propose a randomized controlled effectiveness trial to evaluate the integrated clinic-community model of child obesity treatment as compared with routine primary care.

Detailed Description

The purpose of this study is to evaluate how different types of physical activity and nutrition education and support (in addition to normal clinical care) affect children's health. The investigators will be looking at changes in child BMI, physical activity, nutrition, and overall health. The investigators also hope to better understand biological differences in metabolism and the microbiome (the bacteria that grows normally on and in the body) in children with high BMI who are making lifestyle changes.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
327
Inclusion Criteria
  • Child age 5-18 years
  • Child body mass index ≥ 95th %ile
  • Parent can speak and read in English or Spanish
  • Parent ownership of a device that is able to receive and send text messages
Read More
Exclusion Criteria
  • Live farther than a 20-mile radius from the Healthy and Fit program site
  • Endogenous or genetic cause of obesity
  • Taking a medication that causes weight gain
  • Participation in a pediatric weight management program within 12 months
  • Parent or child significant health problem that would limit participation
  • Enrollment is above the max weekly enrollment of 60 participants/week)
  • Reported or planned pregnancy

Opt-out Criteria

• Primary care physician opts patient out of study for reasons including: severe obesity, urgent co-morbidities, parental unwillingness to be contacted by a research assistant, or at physician clinical judgment.

Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
Intervention GroupHearts & ParksPatients in this group will be receiving the Hearts and Parks intervention.
Primary Outcome Measures
NameTimeMethod
Number of subjects enrolled versus number of subjects who meet min. participation criteria12 months

As measured by enrollment logs

Change in z-BMIBaseline, 6 months
Change in molecular pathways dysregulated in pediatric obesityBaseline, 6 months

Stool and blood samples

Physical activityUp to 12 months

child physical activity; objectively tracked with fitness tracker

Change in child fitnessbaseline, 3 months, 12 months

3 minute bench stepping test

Change in Child Quality of Lifebaseline, 3 months, 12 months

Composite score of Sizing Me Up Questionnaires

Change in Body Appreciationbaseline, 3 months, 12 months

Body appreciation scale 13-item questionnaire (1. Never, 2. Seldom, 3. Sometimes, 4. Often, 5. Always)

Change in heart ratebaseline, 12 months
Change in FLASHE Food and Activity Screener ScoresBaseline, 6 months, 12 months

Questionnaire about child and parent nutrition and activity habits

Change in fasting lipid profileBaseline, 6 months, 12 months
Change in fasting glucoseBaseline, 6 months, 12 months
Change in alanine aminotransferase (A1)Baseline, 6 months, 12 months
Change in child quality of life (2)baseline, 3 months, 12 months

PROMIS Questionnaire (not composite score)

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (3)

Duke Children's Primary Care Roxboro Street

🇺🇸

Durham, North Carolina, United States

Durham Pediatrics at North Duke Street

🇺🇸

Durham, North Carolina, United States

Regional Pediatrics - North Durham

🇺🇸

Durham, North Carolina, United States

© Copyright 2025. All Rights Reserved by MedPath