Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 2
- 主要终点
- Visual acuity
研究概览
简要总结
Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.
详细描述
Spectral domain optical coherence tomography (SD-OCT) was used to calculate the mean length of photoreceptor cone outer segment tips (COST) defect on 1, 3, 6, 9, and 12 months after macular hole surgery. The correlation between the mean length of COST defect and the BCVA was determined. Prognostic factors might have influenced for COST repair was also evaluated by multivariable analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •macular hole patients with surgically-closed hole
排除标准
- •macular hole patients failed to close hole
- •presence of retinal diseases including a treated rhegmatogenous retinal detachment, diabetic retinopathy, and high myopia with an axial length >27.0mm or refractive error > -8.0 diopters(D).
- •patients who were not followed at least 6 months
研究组 & 干预措施
Eyes with macular hole
干预措施: Vitreous surgery for macular hole (Procedure)
结局指标
主要结局
Visual acuity
时间窗: one year
Preoperative, postoperative 1, 3, 6, 9, 12 months
次要结局
- Integrity of cone outer segment tips line(one year)
研究者
Makoto Inoue
Associate professor
Kyorin University