Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery

Kyorin University1 site in 1 country72 target enrollmentMarch 2008

ConditionsMacular Holes

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Macular Holes
Sponsor: Kyorin University
Enrollment: 72
Locations: 1
Primary Endpoint: Visual acuity
Status: Completed
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.

Detailed Description

Spectral domain optical coherence tomography (SD-OCT) was used to calculate the mean length of photoreceptor cone outer segment tips (COST) defect on 1, 3, 6, 9, and 12 months after macular hole surgery. The correlation between the mean length of COST defect and the BCVA was determined. Prognostic factors might have influenced for COST repair was also evaluated by multivariable analysis.

Registry

clinicaltrials.gov

Start Date

March 2008

End Date

February 2011

Last Updated

13 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Kyorin University

Responsible Party

Principal Investigator

Makoto Inoue

Associate professor

Kyorin University

Eligibility Criteria

Inclusion Criteria

•macular hole patients with surgically-closed hole

Exclusion Criteria

•macular hole patients failed to close hole
•presence of retinal diseases including a treated rhegmatogenous retinal detachment, diabetic retinopathy, and high myopia with an axial length \>27.0mm or refractive error \> -8.0 diopters(D).
•patients who were not followed at least 6 months