Foveal Cone Outer Segment Resumption to Predict Visual Recovery After Macular Hole Surgery
- Conditions
- Macular Holes
- Interventions
- Procedure: Vitreous surgery for macular hole
- Registration Number
- NCT01381965
- Lead Sponsor
- Kyorin University
- Brief Summary
Spectral domain optical coherence tomography (SD-OCT) was used to determine whether the repair of photoreceptor cone outer segment tips defect is significantly correlated with the visual outcomes after macular hole surgery.
- Detailed Description
Spectral domain optical coherence tomography (SD-OCT) was used to calculate the mean length of photoreceptor cone outer segment tips (COST) defect on 1, 3, 6, 9, and 12 months after macular hole surgery. The correlation between the mean length of COST defect and the BCVA was determined. Prognostic factors might have influenced for COST repair was also evaluated by multivariable analysis.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 72
- macular hole patients with surgically-closed hole
- macular hole patients failed to close hole
- presence of retinal diseases including a treated rhegmatogenous retinal detachment, diabetic retinopathy, and high myopia with an axial length >27.0mm or refractive error > -8.0 diopters(D).
- patients who were not followed at least 6 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Eyes with macular hole Vitreous surgery for macular hole -
- Primary Outcome Measures
Name Time Method Visual acuity one year Preoperative, postoperative 1, 3, 6, 9, 12 months
- Secondary Outcome Measures
Name Time Method Integrity of cone outer segment tips line one year The mean length of cone outer segment tips defect on preoperative and postoperative 1, 3, 6, 9, and 12 months with spectral domain optical coherence tomography
Trial Locations
- Locations (1)
Makoto Inoue
🇯🇵Mitaka, Tokyo, Japan