A clinical trial to study of analgesic and hemodynamic effect of nalbuphine vs fentanyl, a randomized double blind Interventional Study On Cardiac Surgical Patients
Not Applicable
- Conditions
- Health Condition 1: I39- Endocarditis and heart valve disorders in diseases classified elsewhere
- Registration Number
- CTRI/2019/10/021537
- Lead Sponsor
- Department of anesthesiologySMS medical college jaipur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Either sex
2. Age group 18-65yrs
3 .Body weight 40-70kg
4. ASA Grade II &lll
5. Scheduled for cardiac surgery on cardiopulmonary bypass
Exclusion Criteria
1.Patients not willing to participate in study
2.Uncooperative patients
3.Patients with history of drug allergy
4.Patients with pre-existing, Asthma, Renal or Hepatic dysfunction
5.Morbid obese patient
6.Pregnancy/Lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare hemodynamic variables from baseline at different time interval in both groups. <br/ ><br>Heart rate <br/ ><br>Systolic blood pressure <br/ ><br>Diastolic blood pressure <br/ ><br>Mean Arterial Pressure <br/ ><br>central venous pressure <br/ ><br> <br/ ><br>Timepoint: Data will be recorded baseline (before induction), just after intubation, 5 min and 15 min, 30 min after intubation nd after that 5 min before going on pump, 5 min after going on pump, every 30 min till shifted to icu.
- Secondary Outcome Measures
Name Time Method 1.To asses and compare BIS guided total requirement of analgesic drug in bothgroups <br/ ><br>2.To assess and compare the time required for first rescue analgesic in both group in postoperative period after extubation according to VAS score. <br/ ><br>3.To compare side effects and complications of both drugs. <br/ ><br>Timepoint: After extubation ,post operative analgesia evaluted by visual analogue scale (VAS)in every 30 mins till vas more then 3