NCT03296761UnknownNot Applicable
Endothelial Cell Specific Molecule-1 (ESM-1): a Novel Biomarker for ARDS Endothelial Injury
Jingyuan,Xu1 site in 1 country70 target enrollmentStarted: November 1, 2017Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- mortality
Study Overview
Brief Summary
To observe the changes of plasma ESM-1 levels in patients with ARDS, and to explore its clinical significance.
Detailed Description
70 patients who diagnosed as ARDS were included in this study. Then keep blood samples from these patients in the first day, the third day and the seventh day, detect ESM-1 level in plasma by ELISA. Record Severity of illness and survival status of every patient within 28 days. Objective to evaluate the correlation between the level of ESM-1 in plasma and the prognosis of the patients.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients admitted to ICU diagnosed of ARDS (Berlin definition）in 48h
- •Patients age between 18 years old and 80 years.
- •Exclusion Criteria：
- •Pregnant women,
- •Patients with malignant tumor,
- •Immunosuppression or immunocompromised patients.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
mortality
Time Frame: 28-day
Secondary Outcomes
No secondary outcomes reported
Investigators
Jingyuan,Xu
chief doctor
Southeast University, China
Study Sites (1)
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