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临床试验/NCT02883231
NCT02883231Unknown不适用

Plasma Level of Mitochondrial DNA in Patients With ARDS and Its Clinical Significance

Chun Pan1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2016年4月最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
60
试验地点
1
主要终点
mortality

研究概览

简要总结

To observe the changes of plasma mitochondrial DNA (mtDNA) levels in patients with ARDS, and to explore its clinical significance.

详细描述

60 patients who diagnosed as ARDS were included in this study.Then keep blood samples from these patients in the first day、the third day and the sveventh day,detect the mitochotndrial DNA level in plasma by real-time quantitative PCR. Recored Severity of illness and survival status of every patient within 28 days.Objective to evaluate the correlation between the level of mitochondrial DNA in plasma and the prognosis of the patients.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients admitted to ICU diagnosed of ARDS (Berlin criteria),
  • Patients age between 18 years old and 80 years.

排除标准

  • Pregnant women,
  • Patients with malignant tumor,
  • Immunosuppression or immunocompromised patients.

结局指标

主要结局

mortality

时间窗: 28-day

次要结局

未报告次要终点

研究者

发起方
Chun Pan
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Chun Pan

attending doctor

Southeast University, China

研究点 (1)

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