The Effect of Cataract Extraction on the Contractility of Ciliary Muscle
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- ultrasound biomicroscopic findings (ciliary body axial length)
研究概览
简要总结
The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.
详细描述
The functional changes in the ciliary body in presbyopia are not only important in a study of the mechanism for presbyopia but are also a key to various procedures or devices used to restore accommodation. Therefore, it is becoming increasingly important to quantify the in vivo accommodative changes in the aging ciliary muscle with and without a lens. We are going to evaluate the changes in the pilocarpine-induced contractility of the ciliary muscle in eyes with presbyopia before and after cataract extraction using ultrasound biomicroscopy (UBM).UBM will be performed with and without instilling 2 % pilocarpine, as well as before and 2 months after cataract extraction. Images of the ciliary body will be compared visually using Adobe Photoshop 7.0.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age : same or more than 55 years
- •Patients with senile cataract who are going to get cataract surgery
排除标准
- •Age : less than 55 years
- •Previous ocular disease other than cataract.
研究组 & 干预措施
1
ultrasound biomicrocopic examinations and pilocarpine instillation
干预措施: UBM with pilocarpine in presbyopia (Other)
结局指标
主要结局
ultrasound biomicroscopic findings (ciliary body axial length)
时间窗: 2 months before and after surgery
次要结局
未报告次要终点