ACTRN12608000301369已完成未知
Metabolic and Neurobiological changes after Continuous Positive Airway Pressure (CPAP) treatment for Obstructive Sleep Apnea (OSA)
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- Male
入选标准
- •1. Males aged 18 years or above.
- •2. Moderate to severe obstructive sleep apnea with respiratory disturbance Index (RDI) =20/hr and inclusive of =3% desaturation (RDI >=20 and ODI >=15)
- •3. Written informed consent
- •4. Good general health as defined as men who are community dwelling, with no significant uncontrolled medical problems who are independent in activities of daily living.
- •5. Medical history and physical examination indicating no clinical evidence for significant and uncontrolled cardiovascular (ischemic, hypertension), diabetes, renal, liver, prostate or any other disease.
排除标准
- •1. Severe OSA (minimum oxygen saturation < 65% or RDI > 80) requiring immediate treatment due to severity or increased associated risk (eg Transport worker)
- •2. Psychiatric disorders or drug abuse unless well controlled
- •3. Chronic medical conditions likely to interfere with or influence study treatment or safety unless well controlled
- •4. Contradictions to CPAP therapy
- •5. Any other condition likely, in the judgment of the investigator, that makes the patient unable to complete safely, or otherwise unsuitable for the study
- •6. Shift workers
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