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Clinical Trials/ACTRN12608000301369
ACTRN12608000301369
Completed
未知

Metabolic and Neurobiological changes after Continuous Positive Airway Pressure (CPAP) treatment for Obstructive Sleep Apnea (OSA)

Sydney South West Area Health Service0 sites60 target enrollmentJune 17, 2008
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ConditionsObstructive Sleep ApneaRespiratory - Sleep apnoea

Overview

Phase
未知
Intervention
Not specified
Conditions
Obstructive Sleep Apnea
Sponsor
Sydney South West Area Health Service
Enrollment
60
Status
Completed
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
June 17, 2008
End Date
TBD
Last Updated
6 years ago
Study Type
Interventional
Sex
Male

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Males aged 18 years or above.
  • •2\. Moderate to severe obstructive sleep apnea with respiratory disturbance Index (RDI) \=20/hr and inclusive of \=3% desaturation (RDI \>\=20 and ODI \>\=15\)
  • •3\. Written informed consent
  • •4\. Good general health as defined as men who are community dwelling, with no significant uncontrolled medical problems who are independent in activities of daily living.
  • •5\. Medical history and physical examination indicating no clinical evidence for significant and uncontrolled cardiovascular (ischemic, hypertension), diabetes, renal, liver, prostate or any other disease.

Exclusion Criteria

  • •1\. Severe OSA (minimum oxygen saturation \< 65% or RDI \> 80\) requiring immediate treatment due to severity or increased associated risk (eg Transport worker)
  • •2\. Psychiatric disorders or drug abuse unless well controlled
  • •3\. Chronic medical conditions likely to interfere with or influence study treatment or safety unless well controlled
  • •4\. Contradictions to CPAP therapy
  • •5\. Any other condition likely, in the judgment of the investigator, that makes the patient unable to complete safely, or otherwise unsuitable for the study
  • •6\. Shift workers

Outcomes

Primary Outcomes

Not specified

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