The Impacts of Aquatic Walking and Land-based Walking Exercise Therapy Programs on Vascular Function, Cardiorespiratory Capacity, Exercise Tolerance, Muscular Strength, and Physical Function in Patients With Peripheral Artery Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 147
- 主要终点
- Peripheral Arterial Stiffness
研究概览
简要总结
The purpose of this study was to examine the impacts of a 12-week aquatic walking exercise program on body composition, vascular function, cardiorespiratory capacity, exercise tolerance, muscular strength, and physical function in patients with peripheral artery disease (PAD). The effects of the 12-week aquatic walking exercise program were also compared to the effects of a 12-week land-based walking exercise program.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Peripheral artery disease (ankle-brachial index between 0.6 and 0.9)
- •50-85 years of age
- •Sedentary (less than 1 hour of regular exercise participation per week within the previous year)
排除标准
- •current smoker (smoking within previous 6 months)
- •psychiatric conditions
- •pulmonary disease
- •renal disease
- •thyroid disease
研究组 & 干预措施
Control Group
No exercise intervention
Aquatic walking exercise group 1
The aquatic walking exercise program was performed for 60 minutes per day, 4 times per week for 12 weeks.
The program consisted of a warm-up (10 min) and cool-down (10 min) which included stretching and gait training. The 40-minute main exercise session included 10 minutes of hip flexion-extension, hip abduction-adduction, and knee flexion-extension. The last 30 minutes included water walking (forward, backward).
The program intensity was established using heart rate reserve (HRR). Weeks 1-4 were at 50-60% HRR, weeks 5-8 were at 60-70% HRR, and weeks 9-12 were at 70-85% HRR. Subjects wore a heart rate monitor during the whole exercise training session in order to maintain the designated training intensity.
干预措施: Aquatic walking exercise program group 1 (Other)
Aquatic walking exercise group 2
The aquatic walking exercise program was performed for 60 minutes per day, 4 times per week for 12 weeks.
The program consisted of a warm-up (10 min) and cool-down (10 min) which included stretching and gait training. The 40-minute main exercise session included 10 minutes of hip flexion-extension, hip abduction-adduction, and knee flexion-extension. The last 30 minutes included water walking (forward, backward).
The program intensity was established using heart rate reserve (HRR). Weeks 1-4 were at 50-60% HRR, weeks 5-8 were at 60-70% HRR, and weeks 9-12 were at 70-85% HRR. Subjects wore a heart rate monitor during the whole exercise training session in order to maintain the designated training intensity.
干预措施: Aquatic walking exercise program group 2 (Other)
Land-based walking exercise group
The land-based walking exercise program was performed for 60 minutes per day, 4 times per week for 12 weeks.
The program consisted of a warm-up (10 min) and cool-down (10 min) which included stretching and gait training. The 40-minute main exercise session included 10 minutes of low-intensity forward, backward, and lateral side-stepping movements on flat group. The remaining 30 minutes included treadmill walking exercise.
The program intensity was established using heart rate reserve (HRR). Weeks 1-4 were at 50-60% HRR, weeks 5-8 were at 60-70% HRR, and weeks 9-12 were at 70-85% HRR. Subjects wore a heart rate monitor during the whole exercise training session in order to maintain the designated training intensity.
干预措施: Land-based walking exercise group (Other)
结局指标
主要结局
Peripheral Arterial Stiffness
时间窗: 12 weeks
Peripheral arterial stiffness was estimated as measurement of femoral-to-ankle pulse wave velocity (meters per second). A higher value represents a worse outcome. Scale range is approximately 7.0 - 14.0 meters per second for healthy populations.
次要结局
- Resting Heart Rate(12 weeks)
- Lower Body Strength(12 weeks)
- Exercise Tolerance - Walking Capacity(12 weeks)
- Upper Body Strength(12 weeks)
- Medical Outcomes Study Short-Form 36 General Health Survey for Physical Function(12 weeks)
- Body Composition(12 weeks)
- Systolic Blood Pressure(12 weeks)
- Resting Metabolic Rate(12 weeks)
- Cardiorespiratory Capacity(12 weeks)
- Lower Body Flexibility(12 weeks)
- Diastolic Blood Pressure(12 weeks)
- Systemic Arterial Stiffness(12 weeks)
- Time to Onset of Claudication(12 weeks)
研究者
Won-mok son
Principal Investigator
Pusan National University