A prospective observational study on the association between preoperative frailty and tourniquet induced hemodynamic changes in the elderly patients undergoing orthopedic lower limb surgery with spinal anesthesia
Not Applicable
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0008144
- Lead Sponsor
- Ewha Womans University Seoul Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 72
Inclusion Criteria
Patients aged 65 years or older who are scheduled for orthopedic lower extremity surgery under spinal anesthesia
Exclusion Criteria
American Society of Anesthesiologist Physical status classification IV or higher, Contraindication of spinal anesthesia, arrhythmia, pacemaker implantation, angiotensin-converting enzyme inhibitor or angiotensin-2 receptor blocker, patients with preoperative hypovolemia, preoperative hypotension (mean arterial pressure less than 65 mmHg), patients using vasopressors, patients undergoing dialysis, patients with autonomic nervous system disease, patients whose quadriceps muscle thickness cannot be measured.
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of hypotension after tourniquet deflation
- Secondary Outcome Measures
Name Time Method Severity and duration of hypotension after tourniquet deflation;Type and dose of administered drug when hypotension occurs after tourniquet deflation;Relationship between changes in hemodynamic parameters and hypotension before and after tourniquet decompressio;Arterial blood gas analysis at 5 minutes after tourniquet deflation;Complication such as decreased oxygen saturation during recovery in the post anesthetic care unit;Thickness of the quadriceps muscle on ultrasound sono and thigh circumference at the corrsponding site.