Effect of combined training exercises on fatigue and gait pattern in persons with relapsing-remitting multiple sclerosis

Not Applicable

Completed

• Conditions: Multiple Sclerosis; Physical Medicine / Rehabilitation - Physiotherapy; Neurological - Multiple sclerosis

• Registration Number: ACTRN12615000449538
• Lead Sponsor: Guillermo Izquierdo Ayuso

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-05-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1) Persons with clinically definite Multiple Sclerosis relapsing-remiting, and an Expanded Disability Status Scale Score (EDSS) between 0-4.5
2) Fatigue is one of the most disabling symptoms for their activities daily living performance, with the Fatigue Severity Scale (FSS) score greater than or equal to 4

Exclusion Criteria

1) MS relapse during three month immediately prior to study onset, or during the study
2) cognitive impairment that would interfere with the participating in the study
3) co morbidity that prevents autonomous walking, standing or aerobic exercise, for example, to ride a stationary bicycle
4) pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fatigue.<br><br>Measured by FSS: (Fatigue Severity Scale)<br><br><br>[Baseline and 12 weeks after intervention commencement];Fatigue.<br>Measured by MFIS: (Modified Fatigue Impact Scale). Divided in:<br>MFIS physical <br>MFIS cognitive<br>MFIS phychosocial<br>[Baseline and 12 weeks after intervention commencement]

Secondary Outcome Measures

Name	Time	Method
Mood:<br><br>BDI: (Beck Depression Inventory)<br><br>[Baseline and 12 weeks after intervention commencement];Gait analysis<br><br>We examine gait with GAITRite™ electronic walkway, is a portable gait analysis system and is activated by mechanical pressure as the subject walks on it.<br><br>The gait parameters include in the analysis are: FAP, velocity (cm/sec), cadence (steps/min), step time (s), base of support (cm), swing phase and double support (% gait cycle) and step length difference (cm)[Baseline and 12 weeks after intervention commencement];Health Related Quality of Life:<br><br>MusiQoL Questionnaire[Baseline and 12 weeks after intervention commencement]