serum chemokines levels in vitiligo and correlation with dermoscopic findings and severity of disease.
Not Applicable
- Conditions
- Health Condition 1: L80- Vitiligo
- Registration Number
- CTRI/2023/11/060132
- Lead Sponsor
- Department of Dermatology, Venereology and Leprosy, Government Medical College, Srinagar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age group 12-65 years.
Age and sex matched apparently healthy controls.
Patients with non-segmental vitiligo.
Both males and females will be included.
Exclusion Criteria
Patients receiving systemic treatment in the last 3 months.
Patients receiving narrow band phototherapy (NB UVB).
Patients with any autoimmune disorder such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, systemic lupus erythematosus, patients with type 1 and 2 diabetes mellitus and thyroid disease.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Estimation of Serum levels of CXCL10 in patients and controls.Timepoint: Estimation of Serum CXCL10 Levels, use of dermoscopy in detection of vitiligo activity and stability, vitiligo disease activity score (VIDA),at baseline.Patients will be followed up every 4 weeks, for 16 weeks. At each follow up,VIDA Score and dermoscopy will be done.
- Secondary Outcome Measures
Name Time Method 1.Estimation of serum CXCL10 Levels in patients & controls <br/ ><br>2.VIDA SCORE <br/ ><br>3.VASI SCORE <br/ ><br>4.Dermoscopic Examination of vitiligo to assess the activity of disease.Timepoint: Estimation of Serum CXCL10 Levels, use of dermoscopy in detection of vitiligo activity & stability, vitiligo disease activity score (VIDA),at baseline.Patients will be followed up every 4 weeks, for 16 weeks. At each follow up,VIDA Score & dermoscopy will be done.