To compare the adequacy of the tissue obtained using different suction techniques during endoscopic ultrasound guided biopsy of lymph nodes
Phase 3
- Conditions
- Health Condition 1: K928- Other specified diseases of the digestive system
- Registration Number
- CTRI/2023/06/053953
- Lead Sponsor
- Jayanta Samanta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.age >18 years
2.lymph nodes visualized on EUS and amenable for biopsy
3.Informed consent to participate in the study
Exclusion Criteria
1.Age <18 years,
2.Lymph nodes inaccessible or not visualised with EUS
3.Lymph nodes <10 mm
4.international normalized ratio (INR) >1.5
5.platelet count of <50,000 cells/cubic millimetre
6.unstable clinical conditions or any contraindication for EUS
7.Inability to give informed consent
8.Pregnancy
9.Lesions returned to be not lymph nodes will be dropped out
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint will be the rate of histological adequacy in patients with lymph nodes who underwent EUS-FNB using 22-G FNB needles with the conventional stylet slow-pull or the wet aspiration with varying suction pressure.Timepoint: At baseline - during tissue acquisition
- Secondary Outcome Measures
Name Time Method Blood contamination of specimensTimepoint: At baseline - during tissue acquisition;Comparison of the two techniques in terms of sensitivity, specificity, negative likelihood ratio, positive likelihood ratio & accuracy.Timepoint: At baseline - during tissue acquisition;Specimen adequacyTimepoint: At baseline - during tissue acquisition