Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization

Completed

• Conditions: Pediatric ALL; Molar Incisor Hypomineralization; Oral Health; Dental Plaque; Child, Only; Dental Caries; Dental Diseases

• Registration Number: NCT05779332
• Lead Sponsor: Recep Tayyip Erdogan University Training and Research Hospital

Brief Summary

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).

Detailed Description

Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL). The aim of this study was to determine the prevalence, etiology and impacts of MIH on oral health status and OHRQoL.

Six hundred and fifty-five parents and their children aged 9 years were included in the study. After parents completed the questionnaire about the etiology of MIH, children's OHRQoL was measured by the Child Perceptions Questionnaire (CPQ8-10). Children were evaluated for presence and severity of MIH, dental caries experience and oral hygiene status. Qualitative data were analyzed with the Pearson chi-square and Fisher's exact tests. For the quantitative data, if the normal distribution was not satisfied, Kruskal Wallis/Mann-Whitney U tests were used. Also, Binominal logistic regression analysis was performed and p\<0.05 was statistical significant.

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Study Timeline

• Study Start: 2020-02-01
• Primary Completion: 2020-04-30
• Study Completion: 2020-06-15
• Study First Submitted: 2023-01-19
• Status Verified: 2023-03
• Study First Submitted QC: 2023-03-09
• Last Update Submitted: 2023-03-09
• Study First Posted: 2023-03-22
• Last Update Posted: 2023-03-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 655

Inclusion Criteria

• Being 9-year-old,
• Mentally and physically capable of completing the questionnaire,
• Presence of fully erupted 4 permanent molars and 8 permanent incisors.

Exclusion Criteria

• Children were receiving orthodontic treatment during the examination,
• Children had enamel hypoplasia or developmental defects,
• Children had amelogenesis imperfecta or dental fluorosis.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the impacts of MIH on OHRQoL.	up to six months	The impact of MIH on quality of life (OHRQoL) was measured with the Child Perception Questionnaire (CPQ8-10).
To determine the prevalence and etiology of MIH.	up to four months	A questionnaire was applied to the parents about the etiological factors and the prevalence of MIH was determined by oral examination.
To evaluate the impacts of MIH on oral health status.	up to six months	Oral health was evaluated by recording dmft (decayed, missing and filled teeth) and plaque index values.

Trial Locations

Locations (1)

Sema Aydinoğlu; 🇹🇷 Rize, Turkey