Treatment of Gingival Recession Using Mesenchymal Stem Cells

Phase 1

Completed

• Conditions: Gingival Recession

• Registration Number: NCT04434794
• Lead Sponsor: Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus

Brief Summary

Treatment of patients with gingival recession by injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel

Detailed Description

Treatment of patients with gingival recession by injection of autologous adipose-derived mesenchymal stem cells mixed with collagen gel (1×106cells/0.2 ml). The volume of the mixture is divided into 4 equal injections in the gingival region of one tooth (one place injection volume is 0.05 ml of mixture).

Study Timeline

• Study Start: 2018-01-01
• Primary Completion: 2019-12-31
• Study Completion: 2019-12-31
• Status Verified: 2020-06
• Study First Submitted: 2020-06-13
• Study First Submitted QC: 2020-06-13
• Last Update Submitted: 2020-06-13
• Study First Posted: 2020-06-17
• Last Update Posted: 2020-06-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

-gingival recession

Exclusion Criteria

• pregnancy
• breast-feeding
• acute and chronic infectious diseases: HIV, viral hepatitis, tuberculosis
• mental disorders

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
number of patients cured	1 month	number of patients cured

Trial Locations

Locations (1)

Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus; 🇧🇾 Minsk, Belarus