Evaluation of the therapeutic effect of buspirone in improving the dysphagia of patients with ineffective esophageal motility.

Phase 3

Recruiting

• Conditions: Condition 1: Ineffective esophageal motility. Condition 2: Dysphagia.; Motility disorders of oesophagus; Dysphagia; DA21; R13.1

• Registration Number: IRCT20210418051005N1
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 June 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Ineffective esophageal motility
Age between 18 and 70
Consent
Patient with symptom

Exclusion Criteria

Cancer
Mechanical obstruction
Eosinophilic esophagitis
Diabetes
Opium addiction
Collagen vascular disease
Muscle disorders

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mayo Score. Timepoint: Before intervention and then after 30 days. Method of measurement: Mayo Score.;Esophageal sphincter (LES) resting pressure. Timepoint: Before intervention and then after 30 days. Method of measurement: Manometer.;Distal contractile integral pressure. Timepoint: Before intervention and then after 30 days. Method of measurement: Manometer.;Integrated Relaxation Pressure (IRP). Timepoint: Before intervention and then after 30 days. Method of measurement: Manometer.