EUCTR2006-001125-26-GB
Active, not recruiting
Phase 1
A randomised controlled trial of oral l-arginine supplementation on platelet and endothelial function and walking distance in patients with peripheral arterial disease - L-ARGININE IN PAD
niversity of Aberdeen0 sites56 target enrollmentStarted: July 23, 2006Last updated:
Overview
- Phase
- Phase 1
- Status
- Active, not recruiting
- Sponsor
- niversity of Aberdeen
- Enrollment
- 56
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •All patients must be able to give informed consent, have an ABPI\<0\.8 and be on a statin and aspirin. If patients are not on these medications they will be commenced and enrolled 6 weeks later. We wish to determine the adjuvant effects of L\-arginine in patients with PAD on what is considered to be routine medical therapy. All patients in this study will attend our nurse led claudication clinic and strict attention will be paid to secondary risk factor prevention as per our local guidelines.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •Patients with rest pain or ulceration, liver impairment or abnormal platelet count or diabetes and those on clopidogrel, warfarin or non\-steroidal anti\-inflammatory drugs other than aspirin.
Investigators
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