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临床试验/NCT05482061
NCT05482061已完成不适用

Predictors of Treatment Failure Pain Among Patients Gunshot Wounds

Bogomolets National Medical University1 个研究点 分布在 1 个国家目标入组 2,215 人开始时间: 2022年2月24日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
2,215
试验地点
1
主要终点
visual analog scale

研究概览

简要总结

In patients with gunshot wounds during hostilities in Ukraine, 76.9% have negative results of pain treatment, which leads to its chronicity. Identifying predictors of negative pain outcomes in these patients may improve their treatment outcomes.

详细描述

One of the strongest factors that has a psychological impact on a person is war and conditions in which injury occurs, conditions in which pain occurs. A gunshot wound received during the war in the conditions of hostilities becomes the reason for the indisputable association of pain sensations with the events in which the patient was injured. It is pain and memories, memories and pain that cause the development of states with self-destructive behavior. According to statistics, gunshot wounds account for 54-70%. Gunshot wounds to the chest during anti-terrorist operations/OOS make up 7.4-11.7%, shrapnel wounds prevail here - 72.2%, explosive wounds - 17.5%, bullet wounds - 10.3%, and lethality - 12.2 -25%. According to the data of the Command of the Medical Forces of the Armed Forces of Ukraine, in the structure of gunshot injuries, 64% are injuries to the limbs: of them, 74.8% are soft tissues, 25.2% are gunshot fractures, bone defects are noted in 11.6% of patients, and wounded.

The study of predictors of negative results of pain treatment in patients with gunshot wounds requires in-depth study, because the subjective feelings and emotional experiences experienced by patients during the wounding in combat conditions have their own characteristics. Since in 76.9% of cases it is not possible to achieve a positive result of treatment, the data of our study will play an important role in their treatment.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

性别
Male
接受健康志愿者

入选标准

  • presence of gunshot wounds during hostilities, male gender

排除标准

  • absence of gunshot wounds during hostilities, other sex

结局指标

主要结局

visual analog scale

时间窗: 12 months

from 0 to 10 points (the intensity of pain is determined)

The Hospital Anxiety and Depression Scale

时间窗: 12 months

more than 7 points indicates the presence of anxiety/depression

Mississippi PTSD scale (military version)

时间窗: 12 months

average values of the total score are 76±18 for well-adjusted servicemen, 86±26 for servicemen with mental disorders, 130±18 for PTSD

Didier Bouhassiraa DN4

时间窗: 12 months

the number of points 4 or more indicates that the patient has a neuropathic pain component

Chaban Quality of Life Scale

时间窗: 12 months

assesses quality of life and satisfaction with treatment results up to 56 points - very low 57-66 - low 67-75 - average 76-82 - tall 83-100 is very high

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Vasyl' Horoshko

Principal Investigator

Bogomolets National Medical University

研究点 (1)

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