The Suitability of Sniff Dog as a Tool in Screening Tumors

Recruiting

• Conditions: Neoplasia

• Registration Number: NCT02049645
• Lead Sponsor: Chang-Qing Gao

Brief Summary

Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces. It is hypothesized that sniff dogs may be used as a tool in screening cancer patients in health examination. Trained dogs will sniff serum from participants who are attending the annual health examination to identify potential or high risk subjects, and the results will be compared with the outcome of the traditional health examination, and the high risk subjects will be followed periodically for at least five years.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01
• Study First Submitted: 2014-01-25
• Study First Submitted QC: 2014-01-28
• Study First Posted: 2014-01-30
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-06
• Last Update Posted: 2024-02-08
• Primary Completion: 2024-12-31
• Study Completion: 2026-03

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 4000

Inclusion Criteria

• old than 20 years
• currently without cancer diagnosed with pathological examination
• allow the study team to examine his/her case history and incoming record

Exclusion Criteria

• cancer patients with pathological diagnosis
• who does not allow the study team to examine his/her case history and incoming record

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specificity in screening cancer patients	up to 5 years	The results that obtained from the dogs will be compared with these of the pathological examinations. Sensitivity = the No. of patients identified by the dogs as cancers / the No. of patients suffering from cancer confirmed by pathological examination. Specificity = No. of subjects signaled by the dog as non-cancers / No. of subjects confirmed by pathological examination or the currently used methods as non-cancer subjects or at the end of the study, 5 years later still without cancer.

Secondary Outcome Measures

Name	Time	Method
Behavior patterns of sniff dogs to different diseases	up to 5 years	The behavior (lying before the tank for positive, neglecting the tanks) of the dog will be recorded and compared with the results of the pathological examination.

Trial Locations

Locations (1)

The Third Xiang-Ya Hospital; 🇨🇳 Changsha, Hunan, China