The Suitability of Sniff Dog as a Tool in Screening Tumors-- a Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 4,000
- 试验地点
- 1
- 主要终点
- Sensitivity and specificity in screening cancer patients
研究概览
简要总结
Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces. It is hypothesized that sniff dogs may be used as a tool in screening cancer patients in health examination. Trained dogs will sniff serum from participants who are attending the annual health examination to identify potential or high risk subjects, and the results will be compared with the outcome of the traditional health examination, and the high risk subjects will be followed periodically for at least five years.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •old than 20 years
- •currently without cancer diagnosed with pathological examination
- •allow the study team to examine his/her case history and incoming record
排除标准
- •cancer patients with pathological diagnosis
- •who does not allow the study team to examine his/her case history and incoming record
结局指标
主要结局
Sensitivity and specificity in screening cancer patients
时间窗: up to 5 years
The results that obtained from the dogs will be compared with these of the pathological examinations. Sensitivity = the No. of patients identified by the dogs as cancers / the No. of patients suffering from cancer confirmed by pathological examination. Specificity = No. of subjects signaled by the dog as non-cancers / No. of subjects confirmed by pathological examination or the currently used methods as non-cancer subjects or at the end of the study, 5 years later still without cancer.
次要结局
- Behavior patterns of sniff dogs to different diseases(up to 5 years)
研究者
Chang-Qing Gao
MD PhD
Central South University