Effect of repeated paravertebral injections with local anesthetics and steroids on prevention of post-herpetic neuralgia

Not Applicable

Completed

• Conditions: chest wall herpetic eruption; post-herpetic neuralgia; Anaesthesiology - Pain management; Infection - Other infectious diseases

• Registration Number: ACTRN12614000377639
• Lead Sponsor: Mohamed Y. Makharita

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-04-08
• Study Completion: 2018-01-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

patients over 50 who had chest wall herpetic eruption of less than one week, with moderate and severe pain and received appropriate antiviral therapy.

Exclusion Criteria

patient refusal, eruption of more than one week duration, patients who did not receive appropriate antiviral therapy, patients with mild pain, heavy skin eruption (no healthy area for needle entry) and infection at site of injection. Patients with history of renal, hepatic diseases, coagulopathy, diabetes, steroid therapy, malignancies and patients taking chemo and/or radiotherapy will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Lower the incidence of post herpetic neuralgia which will be evaluated by visual analogue scale[ Assessed before the block (basal), 1 hour after the block, every 3 days for 2 weeks after the procedure and every week for 6 weeks and after 3 and 6 months. ]

Secondary Outcome Measures

Name	Time	Method
Pain severity was assessed using Visual Analogue Scale (VAS), (10 cm unmarked line in which 0 = no pain and 10 cm=worst pain imaginable[Before the block (basal), 1 hour after the block, every 3 days for 2 weeks after the procedure and every week for 6 weeks and after 3 and 6 months];Analgesic consumption was assessed by patient self-report[Before the block (basal), 1 hour after the block, every 3 days for 2 weeks after the procedure and every week for 6 weeks and after 3 and 6 months]