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Clinical Trials/NCT05591274
NCT05591274
Terminated
Not Applicable

Modulating Intraoperative Vasectomy Pain Using the SmileyScope Virtual Reality Interface

University of Miami1 site in 1 country120 target enrollmentNovember 17, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Vasectomy
Sponsor
University of Miami
Enrollment
120
Locations
1
Primary Endpoint
Pre-operative Anxiety
Status
Terminated
Last Updated
last year

Overview

Brief Summary

This study will evaluate whether or not wearing a virtual reality (VR) headset reduces pain and anxiety in patients undergoing vasectomy. The headset being used is the SmileyScope virtual reality interface, a device already undergoing study for approval by the U.S. Food and Drug Administration (FDA) to reduce pain and anxiety in patients aged 4 years and older undergoing needle blood draw or injection procedures. In this study, the SmileyScope virtual reality interface is considered an investigational device because it is not yet approved for use in adult males undergoing vasectomy.

Detailed Description

Vasectomy is a safe and effective procedure for permanent sterilization in males. More than 500,000 vasectomies are performed annually in the United States, and that number is expected to grow rapidly in the coming years. The procedure is safe and can be quickly performed in an outpatient setting. Complications of vasectomy are rare, and can include hematoma and infection, spermatic granulomas, and post-vasectomy pain syndrome in rare cases. Like all outpatient surgical procedures where the patient is not under general anesthesia, vasectomies involve intraoperative and immediate post-operative pain. While use of the no-scalpel technique and local anesthetic reduces intraoperative pain, expected operative pain is still one of the main reasons patients cite for not undergoing the procedure. In our current study, the investigators aim to further modulate intraoperative pain using virtual reality goggles. In clinical trials, the SmileyScope device has been shown to reduce procedural pain in the pediatric population during venipuncture or intravenous cannulation. Results from those studies showed a statistically significant reduction in pain during intravenous procedures in the emergency department. This VR headset is undergoing study for approval by the U.S. Food and Drug Administration (FDA) to reduce pain and anxiety in patients aged 4 years and older undergoing needle blood draw or injection procedures. Currently, this device has been granted entrance to the FDA Safer Technologies Program. In this study, the SmileyScope virtual reality interface is considered an investigational device because it is not yet approved for use in adult males undergoing vasectomy. The aim of this study is to investigate whether this same virtual reality modality can be utilized to reduce pain during vasectomies.

Registry
clinicaltrials.gov
Start Date
November 17, 2022
End Date
March 28, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult males 18 years or older who are undergoing elective vasectomy

Exclusion Criteria

  • Have a serious comorbid illness or condition that, in the opinion of the investigator, may compromise the safety or compliance of the subject or preclude successful completion of the study
  • History of chronic pain disorder or chronic narcotic use
  • Significant refractive error, unilateral blindness, epilepsy, or other conditions such as skin infections, cancer, etc. which could compromise the physical function of the headset.

Outcomes

Primary Outcomes

Pre-operative Anxiety

Time Frame: up to 1 day

Anxiety will be measured via the State-Trait Anxiety Inventory (STAI) anxiety score \[Range 20-80; 20 = low anxiety, 80 = high anxiety\]

Post-operative Anxiety

Time Frame: up to 1 day

Anxiety will be measured via the State-Trait Anxiety Inventory (STAI) anxiety score \[Range 20-80; 20 = low anxiety, 80 = high anxiety\]

Subjective Pre-operative Pain

Time Frame: up to 1 day

Pain will be measured via numeric Likert pain scale \[0-10; 0 = no pain, 10 = highest pain\]

Subjective Post-operative Pain

Time Frame: up to 1 day

Pain will be measured via numeric Likert pain scale; compared to baseline pain scale in pre-operative period \[0-10; 0 = no pain, 10 = highest pain\]

Post-procedure Satisfaction

Time Frame: up to 1 day

Satisfaction will be measured via a questionnaire scored by Likert scale. Questionnaire will ask: "How satisfied were you with today's procedure, with 0 being not satisfied at all, and 10 being the most satisfied?" "How helpful was VR in managing your vasectomy today" (0 is least helpful, 10 is most helpful)"

Secondary Outcomes

  • Physiological Intra-operative Heart Rate(up to 1 day)
  • Physiological Intra-operative Skin Temperature(up to 1 day)
  • Physiological Post-operative Oxygen Saturation(up to 1 day)
  • Physiological Intra-operative Oxygen Saturation(up to 1 day)
  • Physiological Post-operative Heart Rate(up to 1 day)
  • Physiological Post-operative Skin Temperature(up to 1 day)

Study Sites (1)

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