Preventing Anemia in Children (6months-30months) in a Malaria Endemic Rural Area in Ghana - A Randomized Double Blind Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 872
- 试验地点
- 1
- 主要终点
- Haemoglobin concentration, Blood Film for malaria parasitaemia, weight/height ratio
研究概览
简要总结
A study that seeks to establish an effective way of preventing anaemia in children at the community level using two known interventions - Iron supplementation and or antimalarial. Children recruited into the study will be assigned to four groups. Those receiving Placebo and Iron, those receiving Placebo and Antimalarial, those receiving Placebo and Antimalarial and those receiving double placebo. The children will be followed up over a period of nine months and their haemoglobin concentration, malaria parasites in their blood and their weight and height will be assessed.
详细描述
I. INTRODUCTION
Anaemia in children is a major problem in developing countries 1. Iron deficiency is believed to be the most common form of anaemia in children. In some countries fortification of some common foods for children with iron has led to a decrease in morbidity and mortality associated with iron deficiency anemia.2 In malaria endemic areas, anaemia in children is made worse by incidence of malaria.
Brief Background of the District
Berekum District is one of the thirteen administrative districts in the Brong Ahafo Region of Ghana it has a total surface area of 1094.2 sq.km. The estimated population based on the 2000 census with a growth rate of 2.5% is approximately 102,914 for the year 2004.Male to female ratio in the district is 1:1.1. The inhabitants are mainly Brongs with other ethnic groups from all over the country. 55.3% of the population live in the rural area.
II. PROBLEM ANALYSIS
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- Double
入排标准
- 年龄范围
- 6 Months 至 30 Months（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All children living in Berekum District who are between 6months- 30months
排除标准
- •All Children living in Berekum District between 6months- 30months who are G6PD Deficient
结局指标
主要结局
Haemoglobin concentration, Blood Film for malaria parasitaemia, weight/height ratio
次要结局
- Incidence of vaccine preventable diseases like measles whooping cough(pertussis)