The Rate and Predictors of Vaginal Bleeding Among Women With Placenta Previa

Not yet recruiting

• Conditions: Placenta Previa; Antepartum Hemorrhage; Vaginal Bleeding

• Registration Number: NCT05645848
• Lead Sponsor: Assiut University

Brief Summary

Placenta previa is usually diagnosed when the placenta implanted in the lower uterine segment, thus partially or totally overlying the internal os . It occurs with an incidence of 0.3-0.5%. It is associated mainly with prior caesarean delivery . The condition is frequently complicated by invasion of placental villi beyond the decidua basalis causing placenta accreta . Placenta previa is a major cause of massive haemorrhage during pregnancy and after delivery . The antepartum bleeding from placenta previa- can be life-threatening, thus, the prediction of this bleeding is of great importance . It is important to distinguish between women at high and low risk for antepartum haemorrhage with placenta previa especially at late pregnancy . However, the potential risk factors for antepartum haemorrhage in women with placenta previa have not been thoroughly examined.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-11-04
• Status Verified: 2022-12
• Study Start: 2022-12
• Study First Submitted QC: 2022-12-08
• Last Update Submitted: 2022-12-08
• Study First Posted: 2022-12-12
• Last Update Posted: 2022-12-12
• Primary Completion: 2024-12
• Study Completion: 2025-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 250

Inclusion Criteria

• Pregnant women ≥ 28 weeks.
• Diagnosed to have placenta previa by ultrasound

Exclusion Criteria

• Women with complicated pregnancies (e.g. preeclampsia, diabetes mellitus and cardiac, renal, antiphospholipid syndrome).
• Women with premature rupture of membrane.
• Women who will refuse to participate.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The rate of vaginal bleeding in women presented by placenta previa at third trimester of pregnancy.	Through study completion, an average of 1 and half year	The rate of vaginal bleeding in women presented by placenta previa at third trimester of pregnancy.

Secondary Outcome Measures

Name	Time	Method
Identification of the potential clinical and ultrasonographic predictors of antepartum hemorrhage in women with placenta previa at third trimester of pregnancy	through study completion, an average of 1 and half year	The result that the investigators will get from the study will help identify predictors of antepartum hemorrhage in pregnant women with placenta previa and hence preventing it, antepartum hemorrhage is a major life threatening complication of the disease wether to the baby or the mother