Hyaluronic Acid Injection Post Arthroscopy - Does it Improve Immediate Function? Double Blind Controlled Prospective Study

Phase 1

• Conditions: Cartilage Injury
• Interventions: Device: Hyaluronic Acid Injection; Drug: Saline Injection

• Registration Number: NCT01442571
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

The proposed research is to examine the effect of injecting a large volume of HA (10cc) at the time of post arthroscopy suture removal (9-11 day post surgery), in patients with cartilage damage of ICRS grade 2 and above in one of the knee compartments.

Detailed Description

Not available

Study Timeline

• Status Verified: 2011-08
• Study First Submitted: 2011-09-04
• Study First Submitted QC: 2011-09-27
• Last Update Submitted: 2011-09-27
• Study First Posted: 2011-09-28
• Last Update Posted: 2011-09-28

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Adult Men and Women, who underwent arthroscopy of the knee with cartilage injury of ICRS grade 2 or higher in one of the compartments (in addition to other injuries such as meniscal tear and cruciate ligament).

Exclusion Criteria

• Patients with known rheumatic disorders.
• Known hypersensitivity to HA.
• Synovial diseases like PVNS, under 18y old.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Hyaluronic Acid Injection, pain, function	Hyaluronic Acid Injection	-
Saline Injection	Saline Injection	-

Primary Outcome Measures

Name	Time	Method
IKDC (the International Knee Documentation Committee)