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临床试验/NCT04134611
NCT04134611已完成不适用

Use of Hyaluronic Acid Injection After Arthroscopic Lateral Release in Patellar Compression Syndrome With Degenerative Cartilage Changes: Randomized Control Trial

Hawler Medical University2 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2017年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
90
试验地点
2
主要终点
Visual analogue score of knee pain

研究概览

简要总结

Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two groups (A and B). Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, and Group B (45 patients) were no injection intraarticular.

详细描述

This study was done by one orthopedic surgeon in two hospitals. Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two matched groups (A and B) regarding the age and gender; Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, 2 weeks after arthroscopy and were followed by VAS of knee pain for one year at (3) months, (6) months and (12) months, and Group B (45 patients) were no injection intraarticular. The study started on June (2017) and ends on March (2020). injection of Hyaluronic acid was used and followed in the same way. All patients presented with anterior knee pain which failed to respond to conservative treatment for 6 weeks or recurrent of symptoms after stopping of conservative treatment which involved changes of life style and NSAID. MRI done for all patients before operation.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
26 Years 至 47 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Lateral patellar compression syndrome

排除标准

  • Patellar instability.
  • Diabetes Mellitus.
  • Previous knee surgery.

结局指标

主要结局

Visual analogue score of knee pain

时间窗: The VAS for knee pain was measured 24 months after operation

Visual analogue score of knee pain describe knee pain from degree 0 where no pain to degree 10 where is severe pain

Kujala score

时间窗: Preoperative assessment and 2 year postoperatively

Kujala score questionnaire up to 100

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sherwan Ahmed Ali Hamawandi

Assistant professor of orthopedic surgery

Hawler Medical University

研究点 (2)

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