Establishing and utilizing different physiological three-dimensional cell cultures from carcinomas of the breast for personalized cancer therapy

Recruiting

• Conditions: C50; Malignant neoplasm of breast

• Registration Number: DRKS00015026
• Lead Sponsor: OncoRay - National Center for Radiation Research in Oncology and Dept. of Radiation OncologyUniversitätsklinikum and Medizinische Fakultät Carl Gustav Carus

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Pretherapeutic;
- Operable status;
- Mamma-Ca: All patients who have one receive adjuvant radio (chemo) therapy;
- Fresh tissue surgical material available for scientific study;
- surgical report and written histology findings from the Görlitz Hospital available;
- general condition WHO 0-2;
- Age = 18 years

Exclusion Criteria

- Systemic medical therapy, radiotherapy or chemoradiotherapy;
- Lack of insight or lack of cooperation

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
3D cell culture establishment and molecular characterization of 3D cell culture systems with and without in vitro therapy.

Secondary Outcome Measures

Name	Time	Method
Survey of clinical pathological characteristics and course of therapy / follow-up with subsequent linking of the molecular data from the 3D cell cultures with the clinical course.