Gut Microbiota Pilot Study

• Conditions: Metabolism; Microbiota
• Interventions: Biological: Gut microbiota

• Registration Number: NCT03892590
• Lead Sponsor: Armed Forces Goyang Hospital

Brief Summary

Microbiota is known to effect metabolism. This is pilot study to get status of microbiota from normal control. It will be compared to data from specific patients in ICU via further study.

Detailed Description

Microbiota is known to effect metabolism. Patients in specific conditions like hypovolemic shock, sepsis might have changes in status of microbiota. This is pilot study to get status of microbiota from normal control. Stable patient who are admitted to ICU for observation will be gathered. Samples will be collected via rectal swab at time of admission and analyzed via Next generation sequencing.

Study Timeline

• Status Verified: 2019-03
• Study First Submitted: 2019-03-26
• Study First Submitted QC: 2019-03-26
• Last Update Submitted: 2019-03-26
• Study First Posted: 2019-03-27
• Last Update Posted: 2019-03-27
• Study Start: 2019-04-01
• Primary Completion: 2020-02-28
• Study Completion: 2020-03-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Older than 17 years old
• Every patients who are admitted to ICU

Exclusion Criteria

• With history of disease such as cancer, Crohn's disease, ulcerative colitis, irritable bowel syndrome
• With history of immunosuppressive agents.
• Initial systolic blood pressure <100
• Initial pulse rate > 100
• Need emergent operation at brain or torso
• Need vasopressor, transfusion

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Stable patient	Gut microbiota	Stable patients who admitted to ICU for observation.

Primary Outcome Measures

Name	Time	Method
Normal microbiota	1day	Status of microbiota of stable patient in ICU