Strength training for reducing disability in schizophrenia

Not Applicable

Recruiting

• Conditions: F20; Schizophrenia

• Registration Number: DRKS00010842
• Lead Sponsor: Klinik für Psychiatrie und Psychotherapie, Klinikum der Universität München

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-07-26
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

informed consent, diagnosis of schizophrenia according to DSM-V, total postive and negative syndrome scale score 75 or lower, reliable contraception in women of child-bearing age

Exclusion Criteria

lack of accountability, substance abuse at screening (except benzodiazepines), serious suicidal risk at screening visit, other relevant interferences of axis 1 according to diagnostic evaluation (MINI), other relevant neurological or other medical disorders, pregnancy or lactation

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
WHO Disability Assessment Schedule, 36-item interview (4 time points: baseline, after 4 weeks, after 12 weeks, after 18 weeks)

Secondary Outcome Measures

Name	Time	Method
muscle strength, isometric maximal test of 4 main muscle groups (3 timepoints: baseline, after 12 weeks, after 18 weeks)<br>-<br>metabolic profile, blood analysis, BMI, waist circumference, blood pressure (3 timepoints: baseline, after 12 weeks, after 18 weeks)<br>-<br>PANSS-score, Positive and negative syndrome scale (3 timepoints: baseline, after 12 weeks, after 18 weeks)<br>-<br>cognition (e.g. Verbal Learning and Memory Test, VLMT) (3 timepoints: baseline, after 12 weeks, after 18 weeks)