Transcranial Magnetic Stimulation (TMS) for CRPS

Not Applicable

Completed

• Conditions: Complex Regional Pain Syndrome (CRPS)
• Interventions: Device: Transcranial Magnetic Stimulation (TMS)

• Registration Number: NCT02067273
• Lead Sponsor: Stanford University

Brief Summary

The purpose of this pilot study is to test the durability of response to Transcranial Magnetic Stimulation (TMS) for the symptoms of Complex Regional Pain Syndrome (CRPS). The investigators will test various methods of TMS for varying lengths of time in a pilot study to investigate what the clinical impact.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-02-13
• Study First Submitted QC: 2014-02-18
• Study First Posted: 2014-02-20
• Primary Completion: 2015-02
• Study Completion: 2015-03
• Results First Submitted: 2017-04-03
• Status Verified: 2017-05
• Results First Submitted QC: 2017-05-11
• Last Update Submitted: 2017-05-11
• Results First Posted: 2017-05-15
• Last Update Posted: 2017-05-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Age 18 or older
• Diagnosis of CRPS (complex regional pain syndrome)
• Average pain level reported on Numerical Rating Scale meets entry criteria
• Ability to perform the experimental task and procedures.

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Exclusion Criteria

• MRI contraindication (metal implants or devices, claustrophobia)
• TMS Contraindication (eg metal implant or devices near the site of stimulation)
• History of epilepsy
• History of a psychological or psychiatric disorder that would interfere with study procedures, at the discretion of the researcher.
• Neurologic illness that would interfere with brain integrity
• Current medical condition or medication use that would interfere with study procedures or data integrity, at the discretion of the researcher.
• Currently pregnant or planning to become pregnant.
• On going legal action or disability claim.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
TMS Intervention for 5 days	Transcranial Magnetic Stimulation (TMS)	Application of Transcranial Magnetic Stimulation (TMS) for up to 5 days
TMS Intervention for 1 day	Transcranial Magnetic Stimulation (TMS)	Application of Transcranial Magnetic Stimulation (TMS) for 1 day

Primary Outcome Measures

Name	Time	Method
Present Pain Intensity	Baseline, post-treatment, one week follow-up	Present pain intensity was reported by participants using a visual analog scale (VAS) from scores ranging from 1-10; lower scores represent less pain, higher scores represent more severe pain.

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Palo Alto, California, United States