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临床试验/NCT06082310
NCT06082310已完成不适用

Biking vs. Running HIIT in Men With Overweight/Obesity: Impact on Oxygen Consumption, Substrate Utilization and Appetite

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2023年1月11日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10
试验地点
2
主要终点
oxygen consumption during the recovery period

研究概览

简要总结

The management of obesity involves hygienic and dietary measures that include appropriate nutrition and an increase in physical activity (PA). Among the various PA modalities that can be recommended, High-Intensity Interval Training (HIIT) is now recognized as a fun and effective program for promoting fat loss. A meta-analysis conducted by our team suggests a potential influence of the mode of HIIT practice (cycling vs. running) on fat mass (FM) loss. In order to better understand the metabolic adaptations following this type of practice, the investigators propose to compare two isoenergetic HIIT sessions (cycling vs. running) in overweight or obese subjects. The objective is to compare post-recovery (+2h) oxygen consumption, substrate utilization, concurrent energy expenditure and post 24h energy intakes.

详细描述

Overweight/obesity, and more specifically intra-abdominal fat mass (FM), are strongly correlated with the development of cardiovascular diseases. High-Intensity Interval Training (HIIT) has emerged as an effective strategy for reducing this detrimental FM. In 2016, AME2P laboratory was the first to demonstrate that HIIT training is more effective than continuous moderate-intensity training (MICT) in promoting the loss of intra-abdominal fat in postmenopausal women. A meta-analysis conducted by AME2P laboratory in 2018, including 39 scientific articles with 617 subjects, confirms the significant effects of HIIT on total and intra-abdominal fat loss in overweight or obese individuals . In addition to the tested modality (HIIT vs. MICT), it seems that the mode of locomotion (HIIT running vs. cycling) may impact body composition differently, with running being more effective for intra-abdominal fat loss and cycling for total FM loss. Cycling primarily involves concentric effort of the lower limbs, while running engages the lower limbs, trunk, and to a lesser extent, the upper limbs, involving both concentric and eccentric muscle contractions. These physiological/biomechanical differences have an impact on metabolic adaptations to exercise and recovery. Thus, at the same relative intensity during continuous exercise, oxygen consumption and energy expenditure are higher in running compared to cycling. Following exercises of intensity greater than 50% of VO2max, excess post-exercise oxygen consumption (EPOC) and lipid oxidation are higher in running compared to cycling. The greater muscle involvement (engaged muscle mass) and the eccentric nature of running (causing muscle damage) are likely responsible for these adaptations.

To better understand changes in body composition following HIIT training in running versus cycling among overweight or obese patients, the investigators propose to compare two isoenergetic HIIT sessions. The objective is to compare post-exercise (+2h) oxygen consumption and substrate utilization. Considering the influence of practice modalities on dietary compensations, the investigators will simultaneously measure spontaneous dietary intakes over the following 24 hours.

Objectives

The main objective is to compare two isoenergetic HIIT sessions: running vs. cycling.

The two tested modalities are as follows:

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Participant)

盲法说明

Data collected on the volunteers will be made anonymous.

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • men with overweight or obesity (BMI between 25 kg/m2 and 35 kg/m2)

排除标准

  • medical contraindications to intense physical activity,
  • painful joints,
  • taking ß-blocker

结局指标

主要结局

oxygen consumption during the recovery period

时间窗: Two hours after the end of the exercise

Determination of oxygen consumption 2 hours after the exercise session (cycling and running). Determination from Metamax (3D Cortex).

次要结局

  • Lipid and carbohydrate oxidation during and after the exercise session (cycling and running).(Measurement during exercise and two hours after the end of the exercise)
  • Energy intakes 24 hours after the exercise(24 hours post exercise)

研究者

发起方
Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
申办方类型
Other
责任方
Sponsor

研究点 (2)

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