ISRCTN15027862已完成不适用
A randomised factorial trial of N-acetylcysteine prophylaxis and iso-osmolar versus low-osmolar contrast media on kidney function in patients at risk of contrast-induced nephropathy following cardiac catheterisation for percutaneous coronary interventions
iverpool Heart and Chest Hospital NHS Trust (UK)0 个研究点目标入组 200 人开始时间: 2009年7月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Male and female patients aged 18 years or over
- •2. Estimated glomerular filtration rate (eGFR) less than 60 ml/m (as calculated by modified Modification of Diet in Renal Disease [MDRD] equation with local laboratory correction factor)
排除标准
- •1. Patients who had coronary angiography or other procedure with contrast exposure (computed tomography pulmonary angiography [CTPA] etc.) within 2 weeks of percutaneous coronary intervention (PCI)
- •2. Unable to consent
- •3. Patient undergoing cardiac surgery
- •4. Cardiogenic shock
- •5. Unlikely to attend for follow-up blood tests
- •6. Presence of non-cardiac illness that might affect life expectancy
- •7. Any previous allergic reaction to contrast media or N-acetylcysteine (NAC)
研究者
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