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Clinical Trials/NCT04932421
NCT04932421
Completed
N/A

Emotion Detectives - Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children: A Randomized Controlled Trial in the Portuguese Population

University of Coimbra1 site in 1 country153 target enrollmentMarch 1, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Anxiety Disorders
Sponsor
University of Coimbra
Enrollment
153
Locations
1
Primary Endpoint
Changes of children's anxiety and depression
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children (UP-C) is a transdiagnostic and emotion-focused cognitive-behavioral group intervention for children aged 6-12 years old with emotion disorders (i.e., anxious and/or mood disorders) and their parents.

UP-C consists of 15 weekly group sessions and unifies cognitive-behavioral, contextual (e.g., mindfulness) and parental training techniques, for parents and children, aimed at reducing the intensity and frequency of strong and aversive emotional experiences in children and their clinical symptomatology.

The present study aims to assess the feasibility, acceptability and efficacy of the UP-C in the Portuguese population in reducing children's anxiety/depression symptoms. It also aims to investigate which mechanisms explain the therapeutic change.

Participants will be recruited at child mental health services and schools from Central Portugal and also through online dissemination of the study.

A randomized controlled trial (RCT) will be conducted in a sample of children aged 6-13 years old with emotional disorders and their parents in order to answer the critical question of whether the UP-C is more efficacious in reducing children's symptomatology than a psychoeducational group intervention (active control group).

Once the eligibility criteria are met (assessed by the project researchers) parents and children will be randomly assigned to one of two study conditions:

  1. experimental group (i.e., children and parents who benefit from the UP-C program).
  2. control group (i.e., children who benefit from a psychoeducational intervention program, named "ABC of Emotions").

Parents and children from both groups will complete several psychometrically robust and developmentally appropriate measures at baseline (T0), mid-treatment (only at week 7 of the UP-C; T1), post treatment (T2) and at 3 months follow-up (T3).

Registry
clinicaltrials.gov
Start Date
March 1, 2021
End Date
November 30, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Brigida Caiado

Dra. , PhD student

University of Coimbra

Eligibility Criteria

Inclusion Criteria

  • Children aged 6-13
  • Primary diagnosis of an anxiety and/or depression disorder
  • Speaking, reading and understanding Portuguese

Exclusion Criteria

  • Diagnosis of a psychotic disorder, bipolar disorder or intellectual disability;
  • Severe current suicidal/homicidal ideation;
  • The child is not on a stable dose of a psychotropic or other type of medication for at least 1 month prior to T0 assessment.

Outcomes

Primary Outcomes

Changes of children's anxiety and depression

Time Frame: Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months

Changes of children's severity of psychopathology and improvement

Time Frame: Baseline, Póst treatment (15 weeks)

Measured with an adaptation of Clinical Global Impression (CGI). The CGI is composed by a severity of illness scale and a scale evaluating changes from the initiation of treatment. Higher scores are indicative of higher severity of psychopathology and lower improvement from the initiation of treatment.

Secondary Outcomes

  • Changes of child anxiety life interference(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's behavioral avoidance(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's negative emotionality(Baseline, Póst-treatment (15 weeks))
  • Changes of children's anxiety sensitivity(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's mindfulness skills(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's psychological flexibility(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's tolerance of negative emotions(Baseline, Mid-treatment (7 weeks), Póst treatment (15 weeks), Follow-up 3 months)
  • Changes of children's emotional expression and emotion awareness(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of parent's anxiety and depression(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks))
  • Changes of parental anxiety, parental overprotection and parental support of children's coping behaviors(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of parental neuroticism(Baseline, Póst-treatment (15 weeks))
  • Changes of parental criticism(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's negative affect(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of children's negative cognitive error(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of shaping of negative emotions(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of mindfulness in parenting(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)
  • Changes of parental inconsistency and permissiveness(Baseline, Mid-treatment (7 weeks), Póst-treatment (15 weeks), Follow-up 3 months)

Study Sites (1)

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