Use of Benzodiazepines and Z Drugs in the Elderly

• Conditions: Chronic Benzodiazepines and Related Drugs Users

• Registration Number: NCT01920581
• Lead Sponsor: Nantes University Hospital

Brief Summary

The aim of this study is to evaluate benzodiazepines and related drugs (zolpidem and zopiclone) usage in an outpatient population of chronic users over 65 years in France using a questionnaire assessing substance dependence according to DSM-IV (Diagnostic and Statistical Manual of mental disorders) international standards.

Detailed Description

1100 patients will be recruited by pharmacists. They will answer to a standardized questionnaire assessing their benzodiazepines or related drugs usage (phone contact).

Pharmacists are recruited by all French Centers For Evaluation and Information on Pharmacodependence (CEIP).

Study Timeline

• Study Start: 2012-02
• Status Verified: 2013-08
• Study First Submitted: 2013-08-08
• Study First Submitted QC: 2013-08-09
• Last Update Submitted: 2013-08-09
• Study First Posted: 2013-08-12
• Last Update Posted: 2013-08-12
• Primary Completion: 2014-02
• Study Completion: 2014-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1100

Inclusion Criteria

• 65 years old or more,
• benzodiazepines or benzodiazepines related drugs treatment for at least three months,
• written consent and without exclusion criteria.

Exclusion Criteria

• no written consent form
• difficulties to understand or speak french

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Dependence according to DSM IV criteria	2 years

Secondary Outcome Measures

Name	Time	Method
withdrawal syndrome	2 years
psychiatric comorbidities	2 years
Dependence scores	2 years

Trial Locations

Locations (11)

CEIP Lyon; 🇫🇷 Lyon, France

CEIP Grenoble; 🇫🇷 Grenoble, France

CEIP Montpellier; 🇫🇷 Montpellier, France

CEIP Bordeaux; 🇫🇷 Bordeaux, France

CEIP Caen; 🇫🇷 Caen, France

CEIP Lille; 🇫🇷 Lille, France

CEIP Marseille; 🇫🇷 Marseille, France

CEIP Nancy; 🇫🇷 Nancy, France

CEIP Toulouse; 🇫🇷 Toulouse, France

CEIP Paris; 🇫🇷 Paris, France

CEIP Nantes; 🇫🇷 Nantes, France