ACTRN12618001784202
Completed
Phase 2
acetylcysteine as an Adjunctive Treatment in treatment-resistant Post-Traumatic Stress Disorder: a randomised controlled trial
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Austin Health
- Enrollment
- 105
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •To be considered for inclusion in this study, participants are required to be aged 18 or over; have the capacity to consent to the study and to follow its instructions and procedures; fulfil the DSM\-5 diagnostic criteria for current PTSD (identified with the CAPS\-5 monthly version); have completed a course of either trauma\-focussed psychotherapy or an antidepressant; and if currently treated with an antidepressant the dose must have been stable for at least 2 weeks.
Exclusion Criteria
- •Participants are ineligible to enter the trial if they have a psychotic illness; known or suspected clinically unstable systemic medical disorder; epilepsy, recent gastrointestinal ulcers; currently use N\-acetylcysteine, selenium or Vitamin E; a history of anaphylactic reaction to N\-acetylcysteine . Female patients cannot be pregnant or lactating, and all participants must agree to using adequate contraception during the trial.
Outcomes
Primary Outcomes
Not specified
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