Articular Sonography: Findings in Healthy Subjects Compared With Rheumatoid Arthritis Patients

Federal University of São Paulo0 sites190 target enrollmentMarch 2010

ConditionsDisorders of Synovium, Multiple Sites Disorders of Subchondral Bone, Multiple Sites Disorders of Cartilage, Hand Joints Arthritis, Rheumatoid Healthy People

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Disorders of Synovium, Multiple Sites
Sponsor: Federal University of São Paulo
Enrollment: 190
Status: Completed
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The purpose of this study is to establish the normality of sonographic synovial measures in joints more affected in rheumatoid arthritis patients and establish, in those joints, a sonographic value of synovium predictive of rheumatoid arthritis.

Detailed Description

Rheumatoid arthritis (RA) is a chronic inflammatory, systemic and auto-imune disorder affecting primarily the joints. In RA, inflammatory synovium causes destruction of cartilage, erosion of the adjacent bone and ultimately loss of function of the affected joint. Newer imaging techniques, such as ultrasound (US), have shown promise in evaluation of RA. Many US scoring system have been used to classify and quantify the synovium, effusion, erosion and cartilage for assessing and monitoring AR. However, its use is considered problematical because there are very few data on normal joints and, at this point, there is no clear definition of excess amount of synovium in normal people.

Registry

clinicaltrials.gov

Start Date

March 2010

End Date

June 2011

Last Updated

14 years ago

Study Type

Observational

Sex

All