The Effect of Placental Transfusion Methods on the Potentially Transfusion Levels of Endothelial Progenitor Cell and CD34+ Hematopoietic Stem Cell
试验速览
- 阶段
- 不适用
- 入组人数
- 96
- 主要终点
- The levels of stem cells
研究概览
简要总结
To measure the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells levels, and placental residual volume by delayed cord clamping, umbilical cord milking or immediate cord clamping in newborns at different gestational weeks.
详细描述
Umbilical cord blood is a rich source of stem cells. Placental transfusion is the transfer of the placental blood to the baby until the cord clamped during the birth. Placental transfusion can be accomplished by delayed cord clamping or umbilical cord milking.
One group will receive 2 minutes of delayed cord clamping, the second group will receive umbilical cord milking and the third group will receive immediate cord clamping. Following the cord clamping, the blood samples will be taken from the placental site of the umbilical cord to measure the stem cells from all subjects and placental residual volume will be measured.
Delivery room conditions, hospitalization (if needed), short-term outcome during hospitalization, prematurity related morbidities (if baby is preterm) will be recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- — 至 3 Minutes（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Born at 24 weeks to 42 weeks infants
排除标准
- •Without parental consent, known congenital anomalies
结局指标
主要结局
The levels of stem cells
时间窗: 18-months
Measurement of the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells
次要结局
- Placental residual volume(18-months)
研究者
Emel Okulu,MD
Principal Investigator
Ankara University