Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.
Not Applicable
- Conditions
- In Vitro FertilizationAssisted Reproductive Techniques
- Interventions
- Procedure: Day 0 denudation and time lapse culture on IVF-oocytes.
- Registration Number
- NCT02222831
- Lead Sponsor
- Regionshospitalet Viborg, Skive
- Brief Summary
The aims of this study are to evaluate:
1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF.
2. the association between PIF status in embryo culture medium and embryo quality assessed by standard subjective parameters and morphokinetic development.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 100
Inclusion Criteria
- Standard IVF treatment
- Body mass Index (BMI) between 18 and 30
- couples in which the male partner has normal sperm concentration and motility according to the World Health Organization (WHO, 2010)
Exclusion Criteria
- Patients with less than four oocytes
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Day 0 - Study arm Day 0 denudation and time lapse culture on IVF-oocytes. Day 0 denudation and time lapse culture on IVF-oocytes.: After insemination the oocytes will subsequently be denuded and cultured in the EmbryoScope (day 0). The embryo culture media will be collected at day 2-5.
- Primary Outcome Measures
Name Time Method Embryo Quality Day 0-5 after oocyte pick-up
- Secondary Outcome Measures
Name Time Method Fertilisation rate Day 1 after oocyte pick-up
Trial Locations
- Locations (1)
The Fertility Clinic Skive
🇩🇰Skive, Denmark