IVF Outcomes Based on Time Lapse Assisted Embryo Selection Versus Non Invasive PGT-A Assisted Embryo Selection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Aneuploidy
- Sponsor
- Assisting Nature
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Time interval to conceive
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
This is a prospective randomised study of the evaluation of the clinical IVF results after time lapse assisted embryo selection versus Non-invasive PGT-A assisted embryo selection in subfertile women.
Detailed Description
A randomized prospective study focusing on subfertile women undergoing IVF treatment followed by embryo transfer on the blastocyst stage. Women assigned to group A proceed to embryo transfer, after time lapse assisted embryo selection, while women of group B after non-invasive PGT-A assisted embryo selection. IVF outcomes, regarding the success rate of the trasnfer and the time required to achieve conception is studied in both groups.
Investigators
Papanikolaou Evaggelos
Papanikolaou Evaggelos, MD, PhD, Fertility Specialist, Scientific Director at Assisting Nature IVF Clinic
Assisting Nature
Eligibility Criteria
Inclusion Criteria
- •Women who followed IVF treatment
- •39 years old or younger
- •Single embryo transfer
- •blastocyst stage cultured embryos
Exclusion Criteria
- •women over the age of 39 years
- •not blastocyst transfer (transfers performed at earlier embryo stage)
- •double embryotransfer
- •women who had invasive PGT-a test
- •women whose embryos were not time-lapse monitored
Outcomes
Primary Outcomes
Time interval to conceive
Time Frame: Up to the pregnancy test after the last embryo transfer of an enrolled patient (Jan 2024)
Time interval required for women to conceive (in months): from OPU day to positive hCG test
Cumulative Live Birth Rate
Time Frame: Up to 38 weeks after the embryo transfer
Cumulative Live Birth Rate achieved after one OPU treatment
Embryotransfers to conceive
Time Frame: Up to the embryotransfer of the last enrolled patient (Dec 2023)
The number of the embryotransfers required for women to conceive
Secondary Outcomes
- Abortion rate(Up to 2nd trimester miscarriages)
- DaC rate(Up to 24 weeks of pregnancy according to Greek Law)