Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain

Not Applicable

Completed

• Conditions: Acute Pain Due to Trauma; Analgesia

• Registration Number: NCT06351137
• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Brief Summary

Prehospital treatment of acute traumatic pain is common in military practice. Analgesics are usually administered intravenously (IV). Research from the civil prehospital environment shows that obtaining IV access can be difficult and time consuming, delaying onset of treatment. The challenges for obtaining IV access in the military prehospital setting are even bigger, for example in combat environments. However, this has not been assessed.

Current guidelines also offer alternative routes of administration for analgesics, for example intranasal (IN) administration. IN administration is a fast, easy and effective route of administration. This study determines whether IN administration of analgesia is faster and leads to increased healthcare provider satisfaction compared to IV administration in patients with acute traumatic pain in a simulated military prehospital environment.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-03-08
• Study Start: 2024-03-13
• Study First Submitted QC: 2024-04-05
• Study First Posted: 2024-04-08
• Primary Completion: 2024-09-10
• Study Completion: 2024-09-10
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-28
• Last Update Posted: 2025-01-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• All navy healthcare personnel attending (simulation) training on prehospital trauma care.

Exclusion Criteria

none

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Time required for administration of analgesic (minutes)	During simulation training (expected <5 minutes)	Time interval starts when healthcare provider grabs the first required item (e.g. tourniquet, nasal atomizer, ampoule) from the medicine bag. Time interval ends upon completed administration of analgesic.

Secondary Outcome Measures

Name	Time	Method
Total time spent on scene (minutes)	During simulation training (expected <10 minutes)	Time interval starts when healthcare provider arrives at the patient. Time interval ends when analgesia has been administered and used materials have been disposed.
Time required for obtaining IV access	During simulation training (expected <5 minutes)	Time interval starts when healthcare provider grabs the first required item (e.g. tourniquet or alcohol wipe) from the medicine bag. Time interval ends when the IV catheter has been taped or flushed (whichever comes last).
Satisfaction of the navy nurse regarding the used route of administration.	Directly after completion of simulation training	This is rated on a 0-10 Likert scale, where 0 represents "extremely unsatisfactory" and 10 represents "extremily satisfactory"
Time required preparing IN administration	During simulation training (expected <0.5 minute)	Time interval starts when healthcare provider grabs the nasal atomizer. Time interval ends when the nasal atomizer has been placed on the syringe.

Trial Locations

Locations (1)

Amsterdam UMC; 🇳🇱 Amsterdam, Noord-Holland, Netherlands