The effect of Levetiracetam and phenobarbital in treatment of neonatal seizures
Phase 3
- Conditions
- Acute neonatal seizure.Epilepsy and recurrent seizures
- Registration Number
- IRCT20090412001808N7
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Term neonates
Age = 28 days
Clinical seizures requiring treatment based on the diagnosis of a neonatalologist
Seizure diagnosis based on pediatric neurologist diagnosis and EEG interpretation
Written informed consent of parents
Exclusion Criteria
Renal failure
Seizures caused by electrolyte disorders such as hypocalcemia and hypoglycemia
Patients whose seizures respond to vitamin B6 administration
Sensitivity to Levetiracetam or phenobarbital
Structure Anomaly
Asphyxia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Seizure. Timepoint: 30 min, 24 hour up to 1 week, 1st month, 2nd month, 3rd month. Method of measurement: Clinical examination and observation of paroxysmal movements of the neonate.
- Secondary Outcome Measures
Name Time Method Sizure recurrence. Timepoint: 30 min, 24 hour up to 1 week, 1st month, 2nd month, 3rd montt. Method of measurement: Clinical examination and observation.