Management of Anemia with Sammoha loha

Not yet recruiting

Conditions: Iron deficiency anemia, unspecified. Ayurveda Condition: PANDUROGAH,

Registration Number: CTRI/2021/01/030510

Brief Summary: purpose of study : â€œA STANDARD COMPARATIVE CLINICAL STUDY ON PANDUROGA W.S.R. TO IRON DEFICINCEY ANEMIA WITH SAMMOHA LOHA OVER FERROUS SULPHATEâ€

Need for the study : Anemia is the most common and intractable nutritional problem in the world today. WHO has estimated that around 2 billion people across the world is suffering from Anemia. Anemia due to iron deficiency is the most prevalent type of Anemia. Iron Deficiency Anemia is one of the most prevalent forms of malnutrition. Globally, 50% of Anemia is attributable to iron deficiency and accounts for approximately 841,000 deaths annually worldwide. Africa and parts of Asia bears 71% of global mortality burden.

The majority of iron deficiency is seen in growing children, adolescents, menstruating women, pregnant women and due to inadequate dietary intake of iron.

As the name denotes the main feature of Panduroga is pandutva. Panduroga as mentioned in classics is a Pitta Pradana Vyadhi. According to Charaka it is one among the Rasavaha Srotodusti. Here there is Raktha Kshaya due to Pitta which reduces the Raktha Poshakamsha of Rasa. The signs and symptoms of Panduroga include Panduta, Shrama, Bhrama, etc. This description avails the correlation of Panduroga with Anemia in modern science. Iron deficiency Anemia is a disease that has similar symptoms Paleness, Weakness, Fatigue, constitutional symptoms, etiology and pathogenesis.

Panduroga and Iron Deficiency Anemia have been studied in parallel to facilitate a better understanding of the disease and to devise a better management. This disease was chosen for the study due to its high incidence. Despite of many programs conducted by various organization and many medicines available for treating Anemia, it still remains as a burning nutritional problem.

Oral iron salts are the most readily available way of replacing iron, ferrous sulphate is most effective and economical oral preparation. But about 10 â€“ 20% patients will develop gastrointestinal side effects related to the ferrous sulphate these range from nausea, epigastric discomfort, vomiting, constipation and diarrhoea. Hence an attempt is made to compare the effect of Sammoha Loha over Ferrous Sulphate.

With the reference of Rasendra Sara Sangraha Sammoha Loha is chosen for the present study. This is indicated in Panduroga and it contains drugs like Pippali, Maricha, Shunti, Chitraka, Amalaki, Vibhitaki, Hritaki, Vidanga, Lohabhasma, Abhrakabhasma and Ghrita. This has properties like bala, varna, agni vardhana, kamala, pandu rogahara, hridroga, shotahara, krimighna, hence the drug is chosen for the trial. Ferrous sulphate is taken as a standard drug for the comparison.

Hypothesis :H0 - Sammoha Loha is not effective in Panduroga.

H1 â€“ Ferrous Sulphate is more effective in Panduroga than Sammoha Loha.

H2 â€“ Sammoha Loha is more effective in Panduroga than Ferrous Sulphate.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

Patient with symptoms of Panduta, Shrama, Bhrama, Arohana ayasa, Dourbalya, Aruchi, Pindkodwestana, Shoonakshi Koota Shota and Gatrashoola. 1. Patients of Panduroga between the age group of 10 â€“ 60 years. 2. Hb% between 6 gm/dl.

Exclusion Criteria

Known cases of Thalassemia, Sickle Cell Anemia, Pernicious Anemia.
Anemia associated with any malignancy.
Patients under chemotherapy and radiation treatment etc.
Patients suffering from DM and HTN.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in subjective parameters and increase in objective parameters	in 2 months

Secondary Outcome Measures

Name	Time	Method
Increase in hemoglobin range and serum ferritin. Reduction in subjective parameters Panduta, Shrama, Bhrama, Arohana ayasa, Dourbalya, Aruchi, Pindakodwestana, Shoonakshi koota, Gatra shoola.	in 2 months

Trial Locations

Locations (1): DGM Ayurvedic Medical College. Gadag
🇮🇳
Gadag, KARNATAKA, India
DGM Ayurvedic Medical College. Gadag
🇮🇳Gadag, KARNATAKA, India
Dr Rajeshawri M S
Principal investigator
9632036382
msrajeshwari312@gmail.com