Lidocaine Spray on an Endoscope to Improve Tolerance to Endoscopy

Completed

• Conditions: C.Medical Procedure; Digestive System; Disorder of Upper Gastrointestinal Tract; Tolerance
• Interventions: Drug: Case Group

• Registration Number: NCT02307773
• Lead Sponsor: Cheju Halla General Hospital

Brief Summary

The investigators tested whether a new method which additional lidocaine spray on the tip of endoscope can increase the tolerance of examinee during endoscopy than conventional pharyngeal anesthesia alone.

Detailed Description

All the patients underwent upper gastrointestinal endoscopy were consecutively enrolled and assigned to case group treated with additional 2 puffs of the 10% lidocaine spray on the tip of endoscope before intubation or control group with conventional pharyngeal anesthesia without further treatment. And the investigators compared their baseline characteristics, past history, sedation or not, and frequency of retching and belching were measured during the endoscopy.

Study Timeline

• Study Start: 2013-11
• Primary Completion: 2014-05
• Study Completion: 2014-05
• Status Verified: 2014-12
• Study First Submitted: 2014-12-01
• Study First Submitted QC: 2014-12-02
• Study First Posted: 2014-12-04
• Last Update Submitted: 2015-01-12
• Last Update Posted: 2015-01-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 497

Inclusion Criteria

• All the patients who underwent upper gastrointestinal endoscopy in Endoscopy Room, Cheju Hall General Hospital.

Exclusion Criteria

• advanced older or younger age (> 90, or < 15 years)
• comorbidities scored greater than III of American Society of Anestheiologists Physical Status Classification System (ASA) score
• history of hypersensitivity reaction to lidocaine
• he pregnant
• therapeutic or emergency endoscopy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Case Group	Case Group	Treated with additional 2 puffs of the 10% lidocaine spray on the tip of endoscope before intubation with conventional pharyngeal anesthesia

Primary Outcome Measures

Name	Time	Method
Frequency of Belching and retching	Participants will be followed for the duration of hospital stay, expected average of 1-2 hours	Belching was defined as release of gas from the digestive tract (mainly esophagus and stomach) through the mouth and retching was defined as reverse peristaltic movement of the stomach and esophagus without vomiting.

Secondary Outcome Measures

Name	Time	Method
Adverse events	Participants will be followed for the duration of hospital stay, expected average of 1-2 hours	Events suspected as Aspiration pneumonia, methemoglobinemia

Trial Locations

Locations (1)

Digestive Disease Center and Department of Internal Medicine, Cheju Halla General Hospital; 🇰🇷 Jeju-si, Jeju Special Self-Governing Province, Korea, Republic of