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Pharmacological Risk Modification for Progression into Symptomatic Dementia: Complete Enumeration Study Utilizing Administrative Claims Record in Kashiwa City

Not Applicable
Conditions
Alzheimer diseases Levy body dementia
Registration Number
JPRN-UMIN000039040
Lead Sponsor
Tokyo Metropolitan geriatric Medical Center and Institute of Gerontology
Brief Summary

In addition to older age and female sex, use of the following medications was significantly associated with NPADM: statins (HR: 0.82; p=0.001), antihypertensives (HR: 0.80; p<0.0001), non-steroidal bronchodilators (HR: 0.728; p=0.002), antidepressants (HR: 1.79; p<0.0001), poststroke medications (HR: 1.45; p=0.002), insulin (HR: 1.34; p=0.046) and antineoplastics (HR: 1.12; p=0.035).

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
44303
Inclusion Criteria

Not provided

Exclusion Criteria

1. All residents in Kashiwa city who are equal to or younger than 76 years old at April 2012 2. All residents who had prescription of anti-dementia medication while between April and June 2012.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ew prescription of anti-dementia medication
Secondary Outcome Measures
NameTimeMethod
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