Serotype Distribution and Antimicrobial Susceptibility of Streptococcus pneumoniae Associated with Invasive Pneumococcal Disease among Children in Japa

Not Applicable

Recruiting

• Conditions: Invasive Pneumococcal Disease

• Registration Number: JPRN-jRCT1030210333
• Lead Sponsor: Abe Machiko

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-22
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1. Patient age is between 2 months and17 years
2. Patient has S. pneumoniae positive culture from normally sterile sites (i.e., blood or cerebrospinal, synovial, pleural or pericardial fluid or bone)
3. Parents/legally acceptable representatives (LAR) is willing and able to give informed consent for participation in the study

Exclusion Criteria

1. Patient has S. pneumoniae positive ear discharge culture related to acute otitis media without bacteremia or S. pneumoniae positive cerebrospinal fluid
2. Patient has S. pneumoniae positive sputum culture related to pneumococcal pneumonia without bacteremia or S. pneumoniae positive cerebrospinal fluid
3. Patient has S. pneumoniae positive culture obtained from the nasopharynx without bacteremia or S. pneumoniae positive cerebrospinal fluid

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Count and percentage of pneumococcal serotypes detected in pediatric IPD patients and the summary of IPD cases

Secondary Outcome Measures

Name	Time	Method
Productivity loss among parents/caregivers of patients diagnosed with IPD