Comparison of the effects of Pramipexole and Gabapentin on the treatment of restless leg syndrome in patients undergoing hemodialysis
Phase 3
- Conditions
- Restless legs syndrome.Restless legs syndromeG25.81
- Registration Number
- IRCT20191106045350N1
- Lead Sponsor
- Qazvin University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients with end-stage chronic renal failure (at least 6 months) under permanent hemodialysis
Having restless legs syndrome (RLS) based on International RLS Study Group (IRSLSS) diagnostic criteria
Moderate to severe RLS based on IRSLSS diagnostic criteria
Exclusion Criteria
Pregnancy
Iron deficiency anemia
Concomitant neurodegenerative diseases such as cerebrovascular accident (CVA) and Parkinson's disease
Lyme disease
Complications such as nausea, vomiting, and abdominal pain due to medication use
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Disease severity. Timepoint: Before the study and after 4 weeks of treatment. Method of measurement: Severity scale based on International Restless Legs Syndrome Study Group (IRSLSS) diagnostic criteria.
- Secondary Outcome Measures
Name Time Method