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Clinical Trials/NCT07285954
NCT07285954
Recruiting
Not Applicable

A Randomized Controlled Trial of a Walking Meditation Intervention (iWalk) to Enhance Resilience in Adults

University of Illinois at Urbana-Champaign1 site in 1 country90 target enrollmentStarted: June 1, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
90
Locations
1
Primary Endpoint
Connor Davidson Resilience Scale for Adults (CD-RISC 25)

Overview

Brief Summary

This study is a randomized controlled trial of the walking meditation intervention (iWalk) program, a multi-component intervention integrating walking meditation, education, and group sessions designed to enhance resilience in individuals with multiple sclerosis (MS).

The objectives are to evaluate:

  1. Recruitment capability and retention rates,
  2. Acceptability and adherence to the intervention,
  3. Feasibility of assessment procedures, and
  4. Preliminary effects on psychological, physiological, and behavioral outcomes.

Detailed Description

The iWalk Program is an 8-week, multi-component behavioral intervention integrating mindfulness-based stress reduction and walking meditation to promote resilience and self-regulation in people with MS. The intervention combines weekly educational content, guided walking meditation, and group reflection delivered both in-person and virtually. Participants in the experimental group will attend three one-hour sessions per week (two via Zoom, one in-person) focusing on mindfulness, interoception, emotional regulation, and positive coping.

The waitlist control group will receive usual care during the trial period and will be offered participation after study completion.

Assessments include psychological questionnaires, electroencephalography (EEG), cognitive tasks, balance testing, and physical activity monitoring using Fitbit and Hexoskin wearable sensors. Data analysis includes assessing quantitative and qualitative changes in resilience, stress, mindfulness, mood, interoceptive awareness, quality of life, and physical activity over 8 weeks.

The total study duration is 10 weeks per participant, including baseline and post-intervention assessments.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 110 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • 18 years or older,
  • clinical diagnosis of a neurodegenerative disease such as multiple sclerosis, Alzheimer's disease, Parkinson's disease, stroke, etc.,
  • have not practiced meditation regularly (e.g., 10 mins per day) and have never attended any meditation classes or community programs,
  • never received meditation training via coaching/certification/life coaching,
  • have internet access,
  • with no severe cognitive impairment, i.e., have a score of ≥ 21 on Modified Telephonic Interview for Cognitive Status (TICS-M),
  • be able to walk with or without an assistive device (Patient determined Disease Steps score ranged from 0-6),
  • are willing to be randomized to an intervention or a control group,
  • are willing to wear Fitbit (a wrist smart watch) for eight weeks,
  • are individuals who are right-handed according to the Edinburgh Handedness Questionnaire,

Exclusion Criteria

  • Participants who cannot speak, read, write, or listen in English.

Outcomes

Primary Outcomes

Connor Davidson Resilience Scale for Adults (CD-RISC 25)

Time Frame: The baseline means assessments done two weeks before the intervention start date. Post-intervention assessments will be conducted two weeks after the intervention. Follow-up 1 is 24 weeks from baseline, and follow-up 2 is 48 weeks from baseline.

Multiple Sclerosis Resilience Scale (MSRS)

Time Frame: The baseline means assessments done two weeks before the intervention start date. Post-intervention assessments will be conducted two weeks after the intervention. Follow-up 1 is 24 weeks from baseline, and follow-up 2 is 48 weeks from baseline.

Wisconsin Card Sorting Test

Time Frame: The baseline means assessments done two weeks before the intervention start date. Post-intervention assessments will be conducted two weeks after the intervention. Follow-up 1 is 24 weeks from baseline, and follow-up 2 is 48 weeks from baseline.

Sustained Attention to Response Task

Time Frame: The baseline means assessments done two weeks before the intervention start date. Post-intervention assessments will be conducted two weeks after the intervention. Follow-up 1 is 24 weeks from baseline, and follow-up 2 is 48 weeks from baseline.

Stroop Task

Time Frame: The baseline means assessments done two weeks before the intervention start date. Post-intervention assessments will be conducted two weeks after the intervention. Follow-up 1 is 24 weeks from baseline, and follow-up 2 is 48 weeks from baseline.

Symbol Digit Modalities Test

Time Frame: The baseline means assessments done two weeks before the intervention start date. Post-intervention assessments will be conducted two weeks after the intervention. Follow-up 1 is 24 weeks from baseline, and follow-up 2 is 48 weeks from baseline.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Chung-Yi Chiu

Associate Professor

University of Illinois at Urbana-Champaign

Study Sites (1)

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