Associations Between Air Pollutants Exposures and Respiratory System Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- Peking University Third Hospital
- Enrollment
- 106
- Primary Endpoint
- Lung Function indices were performed in peking university third hospital
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare. The present study will assess the association between air pollutants and respiratory related parameters to elucidate possible mechanisms.
Investigators
Bei He
Clinical Professor
Peking University Third Hospital
Eligibility Criteria
Inclusion Criteria
- •Long-term residents, aged \>23 and \<82 years
Exclusion Criteria
- •Severe cardiopulmonary diseases, active inflammatory diseases, cancer
Outcomes
Primary Outcomes
Lung Function indices were performed in peking university third hospital
Time Frame: Repeated-measure study was conducted from November,2014 to January,2016,lung function was measured by every four months
Lung Function indices including FEV1(ml), FVC(ml),the ratio of FEV1/FVC et, al.. When we perform data analysis,these parameters will be expressed as the percentage of the predicted values based on the subject-specific sex, age,height and weight.
Secondary Outcomes
- Inflammation related biomarkers were measured by flow cytometry(Repeated-measure study was conducted from November,2014 to January,2016,biomarkers were measured by every four months)