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临床试验/NCT02964117
NCT02964117已完成不适用

Associations Between Air Pollutants Exposures and Respiratory System Study

Peking University Third Hospital0 个研究点目标入组 106 人开始时间: 2014年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
106
主要终点
Lung Function indices were performed in peking university third hospital

研究概览

简要总结

Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare. The present study will assess the association between air pollutants and respiratory related parameters to elucidate possible mechanisms.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
23 Years 至 82 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Long-term residents, aged >23 and <82 years

排除标准

  • Severe cardiopulmonary diseases, active inflammatory diseases, cancer

结局指标

主要结局

Lung Function indices were performed in peking university third hospital

时间窗: Repeated-measure study was conducted from November,2014 to January,2016,lung function was measured by every four months

Lung Function indices including FEV1(ml), FVC(ml),the ratio of FEV1/FVC et, al.. When we perform data analysis,these parameters will be expressed as the percentage of the predicted values based on the subject-specific sex, age,height and weight.

次要结局

  • Inflammation related biomarkers were measured by flow cytometry(Repeated-measure study was conducted from November,2014 to January,2016,biomarkers were measured by every four months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Bei He

Clinical Professor

Peking University Third Hospital

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