Associations Between Air Pollutants Exposures and Respiratory System Study
Completed
- Conditions
- Chronic Obstructive Pulmonary Disease
- Registration Number
- NCT02964117
- Lead Sponsor
- Peking University Third Hospital
- Brief Summary
Epidemiological investigations has suggested exposure to air pollution linked with respiratory disease, especially chronic obstructive pulmonary disease. However, the potential mechanisms of adverse effects remains scare. The present study will assess the association between air pollutants and respiratory related parameters to elucidate possible mechanisms.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 106
Inclusion Criteria
- Long-term residents, aged >23 and <82 years
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Exclusion Criteria
- Severe cardiopulmonary diseases, active inflammatory diseases, cancer
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Lung Function indices were performed in peking university third hospital Repeated-measure study was conducted from November,2014 to January,2016,lung function was measured by every four months Lung Function indices including FEV1(ml), FVC(ml),the ratio of FEV1/FVC et, al.. When we perform data analysis,these parameters will be expressed as the percentage of the predicted values based on the subject-specific sex, age,height and weight.
- Secondary Outcome Measures
Name Time Method Inflammation related biomarkers were measured by flow cytometry Repeated-measure study was conducted from November,2014 to January,2016,biomarkers were measured by every four months Inflammation related factors including IL,TNFa et, al. all biomarkers units are pg/ml.